Product Information

BREZTRI AEROSPHERE 160-9-4.8 MCG is a brand product labeled by AstraZeneca Pharmaceuticals LP, priced at $61.2823 per GM under NDC 00310461612. Its NADAC has been published 296 times since Dec 23, 2020.

FDA first approved this application on Jul 23, 2020.

BREZTRI AEROSPHERE 160-9-4.8 MCG

budesonide, glycopyrrolate, and formoterol fumarate
$61.2823per GM

Strength

160; 4.8; 9 ug/1; ug/1; ug/1

NDC

00310461612

Classification

Brand

Dosage Form

AEROSOL, METERED

Route

RESPIRATORY (INHALATION)

Effective Date

8/19/2026

Approval Type

New Drug (NDA)

FDA Application

NDA212122

FDA Approved

7/23/2020

On Market Since

7/23/2020

Pharmacological Classes

Adrenergic beta2-Agonists
Anticholinergic
Cholinergic Antagonists
Cholinergic Muscarinic Antagonist
Cholinergic Muscarinic Antagonists
Corticosteroid Hormone Receptor Agonists
Corticosteroid
beta2-Adrenergic Agonist

Price Statistics

The NADAC for BREZTRI AEROSPHERE 160-9-4.8 MCG has been published 296 times since Dec 23, 2020, and over the history we have for it it has risen 15.5%. The table below summarizes its recorded NADAC range and movement.

Current price$61.2823 per GM
All-time high$61.3126 (Aug 12, 2026)
All-time low$53.0608 (Sep 22, 2021)
52-week high$61.3126
52-week low$59.4714
Median price$56.2916
Average price$56.7934
Largest weekly change+3.0% (Jan 14, 2026)
Weeks tracked296
Tracking sinceDec 23, 2020

Price History

1W

-0.0%

1M

-0.0%

3M

-0.0%

6M

+0.0%

1Y

+2.9%

3Y

+8.9%

5Y

+15.5%

All

+15.5%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BREZTRI AEROSPHERE 160-9-4.8 MCG?

The current National Average Drug Acquisition Cost (NADAC) for BREZTRI AEROSPHERE 160-9-4.8 MCG, manufactured by AstraZeneca Pharmaceuticals LP, is $61.2823 per GM (NDC 00310461612), effective Aug 19, 2026.

How has the price of BREZTRI AEROSPHERE 160-9-4.8 MCG changed over time?

Over the history we have for it, the NADAC for BREZTRI AEROSPHERE 160-9-4.8 MCG has risen 15.5%. It has been tracked across 296 weekly CMS publications since Dec 23, 2020.

What are the highest and lowest recorded NADAC prices for BREZTRI AEROSPHERE 160-9-4.8 MCG?

Since Dec 23, 2020, the NADAC for BREZTRI AEROSPHERE 160-9-4.8 MCG has ranged from a low of $53.0608 (Sep 22, 2021) to a high of $61.3126 (Aug 12, 2026), with a median of $56.2916 per GM.

Are there cheaper alternatives to BREZTRI AEROSPHERE 160-9-4.8 MCG?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as BREZTRI AEROSPHERE 160-9-4.8 MCG in a comparable dosage form, but none are currently priced below it.

Who manufactures BREZTRI AEROSPHERE 160-9-4.8 MCG?

BREZTRI AEROSPHERE 160-9-4.8 MCG (NDC 00310461612) is labeled by AstraZeneca Pharmaceuticals LP, and CMS classifies it as a brand product.