Product Information
BREZTRI AEROSPHERE 160-9-4.8 MCG is a brand product labeled by AstraZeneca Pharmaceuticals LP, priced at $61.3039 per GM under NDC 00310461612. Its NADAC has been published 302 times since Dec 23, 2020.
FDA first approved this application on Jul 23, 2020.
Strength
160; 4.8; 9 ug/1; ug/1; ug/1
Manufacturer
AstraZeneca Pharmaceuticals LPNDC
00310461612
Classification
Brand
Dosage Form
AEROSOL, METERED
Route
RESPIRATORY (INHALATION)
Effective Date
9/23/2026
Active Ingredients
BUDESONIDE; FORMOTEROL; GLYCOPYRROLATEApproval Type
New Drug (NDA)
FDA Application
NDA212122FDA Approved
7/23/2020
On Market Since
7/23/2020
Pharmacological Classes
Price Statistics
The NADAC for BREZTRI AEROSPHERE 160-9-4.8 MCG has been published 302 times since Dec 23, 2020, and over the history we have for it it has risen 15.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $61.3039 per GM |
|---|---|
| All-time high | $61.3126 (Aug 12, 2026) |
| All-time low | $53.0608 (Sep 22, 2021) |
| 52-week high | $61.3126 |
| 52-week low | $59.4714 |
| Median price | $56.2916 |
| Average price | $56.8827 |
| Largest weekly change | +3.0% (Jan 14, 2026) |
| Weeks tracked | 302 |
| Tracking since | Dec 23, 2020 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
AstraZeneca Pharmaceuticals LP manufacturer profile
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Drug market
budesonide, glycopyrrolate, and formoterol fumarate market comparison
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Therapeutic class
Anticholinergic class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BREZTRI AEROSPHERE 160-9-4.8 MCG?
The current National Average Drug Acquisition Cost (NADAC) for BREZTRI AEROSPHERE 160-9-4.8 MCG, manufactured by AstraZeneca Pharmaceuticals LP, is $61.3039 per GM (NDC 00310461612), effective Sep 30, 2026.
How has the price of BREZTRI AEROSPHERE 160-9-4.8 MCG changed over time?
Over the history we have for it, the NADAC for BREZTRI AEROSPHERE 160-9-4.8 MCG has risen 15.5%. It has been tracked across 302 weekly CMS publications since Dec 23, 2020.
What are the highest and lowest recorded NADAC prices for BREZTRI AEROSPHERE 160-9-4.8 MCG?
Since Dec 23, 2020, the NADAC for BREZTRI AEROSPHERE 160-9-4.8 MCG has ranged from a low of $53.0608 (Sep 22, 2021) to a high of $61.3126 (Aug 12, 2026), with a median of $56.2916 per GM.
Are there cheaper alternatives to BREZTRI AEROSPHERE 160-9-4.8 MCG?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as BREZTRI AEROSPHERE 160-9-4.8 MCG in a comparable dosage form, but none are currently priced below it.
Who manufactures BREZTRI AEROSPHERE 160-9-4.8 MCG?
BREZTRI AEROSPHERE 160-9-4.8 MCG (NDC 00310461612) is labeled by AstraZeneca Pharmaceuticals LP, and CMS classifies it as a brand product.