Product Information

BREZTRI AEROSPHERE 160-9-4.8 MCG is a brand product labeled by AstraZeneca Pharmaceuticals LP, priced at $61.3864 per GM under NDC 00310461639. Its NADAC has been published 284 times since Mar 17, 2021.

FDA first approved this application on Jul 23, 2020.

BREZTRI AEROSPHERE 160-9-4.8 MCG

budesonide, glycopyrrolate, and formoterol fumarate
$61.3864per GM

Strength

160; 4.8; 9 ug/1; ug/1; ug/1

NDC

00310461639

Classification

Brand

Dosage Form

AEROSOL, METERED

Route

RESPIRATORY (INHALATION)

Effective Date

8/19/2026

Approval Type

New Drug (NDA)

FDA Application

NDA212122

FDA Approved

7/23/2020

On Market Since

7/23/2020

Pharmacological Classes

Adrenergic beta2-Agonists
Anticholinergic
Cholinergic Antagonists
Cholinergic Muscarinic Antagonist
Cholinergic Muscarinic Antagonists
Corticosteroid Hormone Receptor Agonists
Corticosteroid
beta2-Adrenergic Agonist

Price Statistics

The NADAC for BREZTRI AEROSPHERE 160-9-4.8 MCG has been published 284 times since Mar 17, 2021, and over the history we have for it it has risen 15.4%. The table below summarizes its recorded NADAC range and movement.

Current price$61.3864 per GM
All-time high$61.4495 (Jul 15, 2026)
All-time low$53.1936 (Mar 17, 2021)
52-week high$61.4495
52-week low$59.2481
Median price$56.4336
Average price$57.0242
Largest weekly change+3.0% (Jan 14, 2026)
Weeks tracked284
Tracking sinceMar 17, 2021

Price History

1W

+0.2%

1M

+0.2%

3M

+0.4%

6M

+0.4%

1Y

+3.3%

3Y

+8.8%

5Y

+15.4%

All

+15.4%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 0% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 0%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of BREZTRI AEROSPHERE 160-9-4.8 MCG?

The current National Average Drug Acquisition Cost (NADAC) for BREZTRI AEROSPHERE 160-9-4.8 MCG, manufactured by AstraZeneca Pharmaceuticals LP, is $61.3864 per GM (NDC 00310461639), effective Aug 19, 2026.

How has the price of BREZTRI AEROSPHERE 160-9-4.8 MCG changed over time?

Over the history we have for it, the NADAC for BREZTRI AEROSPHERE 160-9-4.8 MCG has risen 15.4%. It has been tracked across 284 weekly CMS publications since Mar 17, 2021.

What are the highest and lowest recorded NADAC prices for BREZTRI AEROSPHERE 160-9-4.8 MCG?

Since Mar 17, 2021, the NADAC for BREZTRI AEROSPHERE 160-9-4.8 MCG has ranged from a low of $53.1936 (Mar 17, 2021) to a high of $61.4495 (Jul 15, 2026), with a median of $56.4336 per GM.

Are there cheaper alternatives to BREZTRI AEROSPHERE 160-9-4.8 MCG?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BREZTRI AEROSPHERE 160-9-4.8 MCG, is $61.2823 per GM — about 0% below BREZTRI AEROSPHERE 160-9-4.8 MCG.

Who manufactures BREZTRI AEROSPHERE 160-9-4.8 MCG?

BREZTRI AEROSPHERE 160-9-4.8 MCG (NDC 00310461639) is labeled by AstraZeneca Pharmaceuticals LP, and CMS classifies it as a brand product.