Product Information
LEVOTHYROXINE 50 MCG TABLET is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.0407 per EA under NDC 00378180377. Its NADAC has been published 530 times since Aug 10, 2016.
FDA first approved this application on Jun 5, 2002. Its Orange Book therapeutic-equivalence code is AB1,AB2,AB3,AB4 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 ug/1
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378180377
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
LEVOTHYROXINE SODIUMApproval Type
Generic (ANDA)
FDA Application
ANDA076187FDA Approved
6/5/2002
TE Code
AB1,AB2,AB3,AB4
On Market Since
11/1/2002
Pharmacological Classes
Price Statistics
The NADAC for LEVOTHYROXINE 50 MCG TABLET has been published 530 times since Aug 10, 2016, and over the history we have for it it has declined 88.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0407 per EA |
|---|---|
| All-time high | $0.3503 (Aug 10, 2016) |
| All-time low | $0.0406 (Aug 19, 2026) |
| 52-week high | $0.0524 |
| 52-week low | $0.0406 |
| Median price | $0.2020 |
| Average price | $0.1847 |
| Largest weekly change | +35.8% (Jun 19, 2024) |
| Weeks tracked | 530 |
| Tracking since | Aug 10, 2016 |
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Mylan Pharmaceuticals Inc. manufacturer profile
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Drug market
levothyroxine sodium market comparison
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Therapeutic class
l-Thyroxine class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LEVOTHYROXINE 50 MCG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for LEVOTHYROXINE 50 MCG TABLET, manufactured by Mylan Pharmaceuticals Inc., is $0.0407 per EA (NDC 00378180377), effective Sep 30, 2026.
How has the price of LEVOTHYROXINE 50 MCG TABLET changed over time?
Over the history we have for it, the NADAC for LEVOTHYROXINE 50 MCG TABLET has declined 88.4%. It has been tracked across 530 weekly CMS publications since Aug 10, 2016.
What are the highest and lowest recorded NADAC prices for LEVOTHYROXINE 50 MCG TABLET?
Since Aug 10, 2016, the NADAC for LEVOTHYROXINE 50 MCG TABLET has ranged from a low of $0.0406 (Aug 19, 2026) to a high of $0.3503 (Aug 10, 2016), with a median of $0.2020 per EA.
Are there cheaper alternatives to LEVOTHYROXINE 50 MCG TABLET?
6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LEVOTHYROXINE 50 MCG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures LEVOTHYROXINE 50 MCG TABLET?
LEVOTHYROXINE 50 MCG TABLET (NDC 00378180377) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.