Product Information

ATOVAQUONE-PROGUANIL 250-100 MG TABLET is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $1.6129 per EA under NDC 00378416201. Its NADAC has been published 624 times since Jul 16, 2014.

The Low Outlier badge above means this manufacturer's average price in the atovaquone and proguanil hydrochloride market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

ATOVAQUONE-PROGUANIL 250-100 MG TABLET

atovaquone and proguanil hydrochloride
$1.6129per EA
Low Outlier

Strength

250; 100 mg/1; mg/1

NDC

00378416201

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Last Updated

6/17/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA202362

On Market Since

5/28/2014

Pharmacological Classes

Antimalarial
Antimalarial
Antiprotozoal
Dihydrofolate Reductase Inhibitors

Price Statistics

The NADAC for ATOVAQUONE-PROGUANIL 250-100 MG TABLET has been published 624 times since Jul 16, 2014, and over the history we have for it it has declined 69.6%. The table below summarizes its recorded NADAC range and movement.

Current price$1.6129 per EA
All-time high$5.4053 (Jun 10, 2015)
All-time low$1.2534 (Nov 20, 2024)
52-week high$1.8095
52-week low$1.4983
Median price$2.6656
Average price$3.0008
Largest weekly change+67.1% (Feb 22, 2023)
Weeks tracked624
Tracking sinceJul 16, 2014

Price History

1W

0.0%

1M

+2.9%

3M

+7.7%

6M

-2.3%

1Y

-10.9%

3Y

-19.6%

5Y

-29.4%

All

-69.6%

Generic Alternatives

The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ATOVAQUONE-PROGUANIL 250-100 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ATOVAQUONE-PROGUANIL 250-100 MG TABLET, manufactured by Mylan Pharmaceuticals Inc., is $1.6129 per EA (NDC 00378416201), effective Jun 24, 2026.

How has the price of ATOVAQUONE-PROGUANIL 250-100 MG TABLET changed over time?

Over the history we have for it, the NADAC for ATOVAQUONE-PROGUANIL 250-100 MG TABLET has declined 69.6%. It has been tracked across 624 weekly CMS publications since Jul 16, 2014.

What are the highest and lowest recorded NADAC prices for ATOVAQUONE-PROGUANIL 250-100 MG TABLET?

Since Jul 16, 2014, the NADAC for ATOVAQUONE-PROGUANIL 250-100 MG TABLET has ranged from a low of $1.2534 (Nov 20, 2024) to a high of $5.4053 (Jun 10, 2015), with a median of $2.6656 per EA.

Are there cheaper alternatives to ATOVAQUONE-PROGUANIL 250-100 MG TABLET?

2 NADAC-published products share the same active ingredient, strength, and dosage form as ATOVAQUONE-PROGUANIL 250-100 MG TABLET, but none are currently priced below it.

Who manufactures ATOVAQUONE-PROGUANIL 250-100 MG TABLET?

ATOVAQUONE-PROGUANIL 250-100 MG TABLET (NDC 00378416201) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.