Historical record - last NADAC effective date: 4/17/2024
Product Information
MALARONE 250-100 MG TABLET is a brand product labeled by GlaxoSmithKline LLC, priced at $6.6105 per EA under NDC 00173067501. Its NADAC has been published 126 times since Nov 28, 2013.
FDA first approved this application on Jul 14, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the atovaquone and proguanil hydrochloride market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
250; 100 mg/1; mg/1
Manufacturer
GlaxoSmithKline LLCNDC
00173067501
Classification
Brand
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
4/17/2024
Active Ingredients
ATOVAQUONE; PROGUANIL HYDROCHLORIDEApproval Type
New Drug (NDA)
FDA Application
NDA021078FDA Approved
7/14/2000
TE Code
AB
On Market Since
7/26/2000
Pharmacological Classes
Price Statistics
The NADAC for MALARONE 250-100 MG TABLET has been published 126 times since Nov 28, 2013, and over the history we have for it it has declined 2.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $6.6105 per EA |
|---|---|
| All-time high | $6.7562 (Mar 12, 2014) |
| All-time low | $6.5747 (Mar 19, 2014) |
| Median price | $6.6105 |
| Average price | $6.6128 |
| Largest weekly change | -2.7% (Mar 19, 2014) |
| Weeks tracked | 126 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
+0.5%
5Y
+0.5%
All
-2.2%
Last surveyed Apr 16, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 78% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of MALARONE 250-100 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for MALARONE 250-100 MG TABLET, manufactured by GlaxoSmithKline LLC, is $6.6105 per EA (NDC 00173067501), effective Apr 16, 2025.
How has the price of MALARONE 250-100 MG TABLET changed over time?
Over the history we have for it, the NADAC for MALARONE 250-100 MG TABLET has declined 2.2%. It has been tracked across 126 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for MALARONE 250-100 MG TABLET?
Since Nov 28, 2013, the NADAC for MALARONE 250-100 MG TABLET has ranged from a low of $6.5747 (Mar 19, 2014) to a high of $6.7562 (Mar 12, 2014), with a median of $6.6105 per EA.
Are there cheaper alternatives to MALARONE 250-100 MG TABLET?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ATOVAQUONE-PROGUANIL 250-100 MG TABLET, is $1.4777 per EA — about 78% below MALARONE 250-100 MG TABLET.
Who manufactures MALARONE 250-100 MG TABLET?
MALARONE 250-100 MG TABLET (NDC 00173067501) is labeled by GlaxoSmithKline LLC, and CMS classifies it as a brand product.