Product Information
DOXYLAMINE-PYRIDOXINE 10-10 MG is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $1.2627 per EA under NDC 00378461501. Its NADAC has been published 299 times since Sep 9, 2020.
FDA first approved this application on Jul 6, 2020.
Strength
10; 10 mg/1; mg/1
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378461501
Classification
Generic
Dosage Form
TABLET, DELAYED RELEASE
Route
ORAL
Effective Date
5/20/2026
Active Ingredients
DOXYLAMINE SUCCINATE; PYRIDOXINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA207825FDA Approved
7/6/2020
On Market Since
7/21/2020
Pharmacological Classes
Price Statistics
The NADAC for DOXYLAMINE-PYRIDOXINE 10-10 MG has been published 299 times since Sep 9, 2020, and over the history we have for it it has declined 71.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.2627 per EA |
|---|---|
| All-time high | $5.3468 (Sep 15, 2021) |
| All-time low | $0.9736 (Jul 17, 2024) |
| 52-week high | $1.3056 |
| 52-week low | $1.1573 |
| Median price | $2.0018 |
| Average price | $2.3312 |
| Largest weekly change | +68.5% (Jun 19, 2024) |
| Weeks tracked | 299 |
| Tracking since | Sep 9, 2020 |
1W
N/A
1M
N/A
3M
0.0%
6M
+5.3%
1Y
-2.6%
3Y
-27.5%
5Y
-76.4%
All
-71.2%
Last surveyed May 27, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DOXYLAMINE-PYRIDOXINE 10-10 MG?
The current National Average Drug Acquisition Cost (NADAC) for DOXYLAMINE-PYRIDOXINE 10-10 MG, manufactured by Mylan Pharmaceuticals Inc., is $1.2627 per EA (NDC 00378461501), effective May 27, 2026.
How has the price of DOXYLAMINE-PYRIDOXINE 10-10 MG changed over time?
Over the history we have for it, the NADAC for DOXYLAMINE-PYRIDOXINE 10-10 MG has declined 71.2%. It has been tracked across 299 weekly CMS publications since Sep 9, 2020.
What are the highest and lowest recorded NADAC prices for DOXYLAMINE-PYRIDOXINE 10-10 MG?
Since Sep 9, 2020, the NADAC for DOXYLAMINE-PYRIDOXINE 10-10 MG has ranged from a low of $0.9736 (Jul 17, 2024) to a high of $5.3468 (Sep 15, 2021), with a median of $2.0018 per EA.
Are there cheaper alternatives to DOXYLAMINE-PYRIDOXINE 10-10 MG?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as DOXYLAMINE-PYRIDOXINE 10-10 MG in a comparable dosage form, but none are currently priced below it.
Who manufactures DOXYLAMINE-PYRIDOXINE 10-10 MG?
DOXYLAMINE-PYRIDOXINE 10-10 MG (NDC 00378461501) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.