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Product Information

HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET is a generic product labeled by SpecGx LLC, priced at $0.1379 per EA under NDC 00406012412. Its NADAC has been published 452 times since Sep 13, 2017.

FDA first approved this application on Sep 8, 2000. Its Orange Book therapeutic-equivalence code is AA.

HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET

HYDROCODONE BITARTRATE AND ACETAMINOPHEN
$0.1379per EA
DEA Schedule CII

Strength

325; 7.5 mg/1; mg/1

Manufacturer

SpecGx LLC

NDC

00406012412

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

4/22/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA040405

FDA Approved

9/8/2000

TE Code

AA

On Market Since

9/8/2000

Pharmacological Classes

Opioid Agonist
Opioid Agonists

Price Statistics

The NADAC for HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET has been published 452 times since Sep 13, 2017, and over the history we have for it it has declined 20.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1379 per EA
All-time high$0.1736 (Sep 13, 2017)
All-time low$0.0932 (Dec 18, 2019)
52-week high$0.1522
52-week low$0.1379
Median price$0.1321
Average price$0.1316
Largest weekly change+41.5% (Jan 22, 2020)
Weeks tracked452
Tracking sinceSep 13, 2017

Price History

1W

N/A

1M

N/A

3M

N/A

6M

-1.3%

1Y

-9.4%

3Y

+7.5%

5Y

+13.0%

All

-20.6%

Last surveyed May 6, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 2% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 2%

1 alternative • Same active ingredient

HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET
Generic
00406012401•SpecGx LLC
$0.1354
Save 2%

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Continue researching this drug

Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.

Manufacturer

SpecGx LLC manufacturer profile

See the full portfolio, pricing trend, and other products from this labeler.

Drug market

HYDROCODONE BITARTRATE AND ACETAMINOPHEN market comparison

Compare this molecule across participating manufacturers and inspect the broader market price spread.

Therapeutic class

Opioid Agonist class view

See how this drug behaves alongside other products in the same FDA pharmacologic class.

Trend hub

Latest market trends

Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.

Guide

Understanding NADAC pricing

Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.

Frequently asked questions

What is the NADAC price of HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET, manufactured by SpecGx LLC, is $0.1379 per EA (NDC 00406012412), effective May 6, 2026.

How has the price of HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET changed over time?

Over the history we have for it, the NADAC for HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET has declined 20.6%. It has been tracked across 452 weekly CMS publications since Sep 13, 2017.

What are the highest and lowest recorded NADAC prices for HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET?

Since Sep 13, 2017, the NADAC for HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET has ranged from a low of $0.0932 (Dec 18, 2019) to a high of $0.1736 (Sep 13, 2017), with a median of $0.1321 per EA.

Are there cheaper alternatives to HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET, is $0.1354 per EA — about 2% below HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET.

Who manufactures HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET?

HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET (NDC 00406012412) is labeled by SpecGx LLC, and CMS classifies it as a generic product.