Product Information
CLOMIPRAMINE 25 MG CAPSULE is a generic product labeled by SpecGx LLC, priced at $0.1888 per EA under NDC 00406880601. Its NADAC has been published 574 times since Oct 7, 2015.
FDA first approved this application on Dec 29, 1989. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
SpecGx LLCNDC
00406880601
Classification
Generic
Dosage Form
CAPSULE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
CLOMIPRAMINE HYDROCHLORIDEApproval Type
New Drug (NDA)
FDA Application
NDA019906FDA Approved
12/29/1989
TE Code
AB
On Market Since
6/1/2015
Pharmacological Classes
Price Statistics
The NADAC for CLOMIPRAMINE 25 MG CAPSULE has been published 574 times since Oct 7, 2015, and over the history we have for it it has declined 97.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1888 per EA |
|---|---|
| All-time high | $8.9356 (Apr 13, 2016) |
| All-time low | $0.1694 (Jul 22, 2026) |
| 52-week high | $0.2669 |
| 52-week low | $0.1694 |
| Median price | $2.1461 |
| Average price | $2.7507 |
| Largest weekly change | +59.2% (May 19, 2021) |
| Weeks tracked | 574 |
| Tracking since | Oct 7, 2015 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
SpecGx LLC manufacturer profile
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Drug market
clomipramine hydrochloride market comparison
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Therapeutic class
Tricyclic Antidepressant class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CLOMIPRAMINE 25 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for CLOMIPRAMINE 25 MG CAPSULE, manufactured by SpecGx LLC, is $0.1888 per EA (NDC 00406880601), effective Sep 30, 2026.
How has the price of CLOMIPRAMINE 25 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for CLOMIPRAMINE 25 MG CAPSULE has declined 97.9%. It has been tracked across 574 weekly CMS publications since Oct 7, 2015.
What are the highest and lowest recorded NADAC prices for CLOMIPRAMINE 25 MG CAPSULE?
Since Oct 7, 2015, the NADAC for CLOMIPRAMINE 25 MG CAPSULE has ranged from a low of $0.1694 (Jul 22, 2026) to a high of $8.9356 (Apr 13, 2016), with a median of $2.1461 per EA.
Are there cheaper alternatives to CLOMIPRAMINE 25 MG CAPSULE?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as CLOMIPRAMINE 25 MG CAPSULE in a comparable dosage form, but none are currently priced below it.
Who manufactures CLOMIPRAMINE 25 MG CAPSULE?
CLOMIPRAMINE 25 MG CAPSULE (NDC 00406880601) is labeled by SpecGx LLC, and CMS classifies it as a generic product.