Product Information
DAPTOMYCIN 500 MG VIAL is a generic product labeled by Hospira Inc., priced at $20.7686 per EA under NDC 00409012201. Its NADAC has been published 93 times since Apr 17, 2024.
FDA first approved this application on Jun 21, 2021.
Strength
500 mg/10mL
Manufacturer
Hospira Inc.NDC
00409012201
Classification
Generic
Dosage Form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Route
INTRAVENOUS
Effective Date
1/21/2026
Active Ingredients
DAPTOMYCINApproval Type
New Drug (NDA)
FDA Application
NDA210282FDA Approved
6/21/2021
On Market Since
8/2/2021
Pharmacological Classes
Price Statistics
The NADAC for DAPTOMYCIN 500 MG VIAL has been published 93 times since Apr 17, 2024, and over the history we have for it it has declined 16.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $20.7686 per EA |
|---|---|
| All-time high | $28.3900 (Sep 11, 2024) |
| All-time low | $20.1020 (Oct 22, 2025) |
| 52-week high | $24.2743 |
| 52-week low | $20.1020 |
| Median price | $23.8720 |
| Average price | $23.2457 |
| Largest weekly change | -17.2% (Oct 22, 2025) |
| Weeks tracked | 93 |
| Tracking since | Apr 17, 2024 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
-14.4%
3Y
N/A
5Y
N/A
All
-16.4%
Last surveyed Jan 21, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Hospira Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
DAPTOMYCIN market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Lipopeptide Antibacterial class view
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DAPTOMYCIN 500 MG VIAL?
The current National Average Drug Acquisition Cost (NADAC) for DAPTOMYCIN 500 MG VIAL, manufactured by Hospira Inc., is $20.7686 per EA (NDC 00409012201), effective Jan 21, 2026.
How has the price of DAPTOMYCIN 500 MG VIAL changed over time?
Over the history we have for it, the NADAC for DAPTOMYCIN 500 MG VIAL has declined 16.4%. It has been tracked across 93 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for DAPTOMYCIN 500 MG VIAL?
Since Apr 17, 2024, the NADAC for DAPTOMYCIN 500 MG VIAL has ranged from a low of $20.1020 (Oct 22, 2025) to a high of $28.3900 (Sep 11, 2024), with a median of $23.8720 per EA.
Are there cheaper alternatives to DAPTOMYCIN 500 MG VIAL?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DAPTOMYCIN 500 MG VIAL in a comparable dosage form, but none are currently priced below it.
Who manufactures DAPTOMYCIN 500 MG VIAL?
DAPTOMYCIN 500 MG VIAL (NDC 00409012201) is labeled by Hospira Inc., and CMS classifies it as a generic product.