This NDC is on FDA's drug shortage list (posted Apr 2, 2020)
Reported reason: Demand increase for the drug
Product Information
MIDAZOLAM HCL 5 MG/ML VIAL is a generic product labeled by Hospira Inc., priced at $1.2214 per ML under NDC 00409230801. Its NADAC has been published 174 times since Jan 22, 2014.
FDA first approved this application on Jul 22, 2002. Its Orange Book therapeutic-equivalence code is AP.
Strength
5 mg/mL
Manufacturer
Hospira Inc.NDC
00409230801
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS
Effective Date
8/19/2026
Active Ingredients
MIDAZOLAM HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA075857FDA Approved
7/22/2002
TE Code
AP
On Market Since
6/14/2005
Pharmacological Classes
Price Statistics
The NADAC for MIDAZOLAM HCL 5 MG/ML VIAL has been published 174 times since Jan 22, 2014, and over the history we have for it it has risen 21.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.2214 per ML |
|---|---|
| All-time high | $1.2214 (Aug 19, 2026) |
| All-time low | $0.9764 (Dec 17, 2025) |
| 52-week high | $1.2214 |
| 52-week low | $0.9764 |
| Median price | $1.0035 |
| Average price | $1.0206 |
| Largest weekly change | +6.5% (Mar 18, 2026) |
| Weeks tracked | 174 |
| Tracking since | Jan 22, 2014 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 69% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of MIDAZOLAM HCL 5 MG/ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for MIDAZOLAM HCL 5 MG/ML VIAL, manufactured by Hospira Inc., is $1.2214 per ML (NDC 00409230801), effective Aug 19, 2026.
How has the price of MIDAZOLAM HCL 5 MG/ML VIAL changed over time?
Over the history we have for it, the NADAC for MIDAZOLAM HCL 5 MG/ML VIAL has risen 21.7%. It has been tracked across 174 weekly CMS publications since Jan 22, 2014.
What are the highest and lowest recorded NADAC prices for MIDAZOLAM HCL 5 MG/ML VIAL?
Since Jan 22, 2014, the NADAC for MIDAZOLAM HCL 5 MG/ML VIAL has ranged from a low of $0.9764 (Dec 17, 2025) to a high of $1.2214 (Aug 19, 2026), with a median of $1.0035 per ML.
Are there cheaper alternatives to MIDAZOLAM HCL 5 MG/ML VIAL?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, MIDAZOLAM HCL 50 MG/10 ML VIAL, is $0.3817 per ML — about 69% below MIDAZOLAM HCL 5 MG/ML VIAL.
Who manufactures MIDAZOLAM HCL 5 MG/ML VIAL?
MIDAZOLAM HCL 5 MG/ML VIAL (NDC 00409230801) is labeled by Hospira Inc., and CMS classifies it as a generic product.
Is MIDAZOLAM HCL 5 MG/ML VIAL in shortage?
Yes — NDC 00409230801 is currently listed in FDA's drug shortage database (posted Apr 2, 2020). Reported reason: Demand increase for the drug.