This NDC is on FDA's drug shortage list (posted Apr 2, 2020)
Product Information
MIDAZOLAM HCL 50 MG/10 ML VIAL is a generic product labeled by Hospira Inc., priced at $0.3817 per ML under NDC 00409259605. Its NADAC has been published 188 times since Jan 22, 2014.
FDA first approved this application on Jun 20, 2000. Its Orange Book therapeutic-equivalence code is AP.
Strength
5 mg/mL
Manufacturer
Hospira Inc.NDC
00409259605
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS
Effective Date
8/19/2026
Active Ingredients
MIDAZOLAM HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA075293FDA Approved
6/20/2000
TE Code
AP
On Market Since
11/3/2005
Pharmacological Classes
Price Statistics
The NADAC for MIDAZOLAM HCL 50 MG/10 ML VIAL has been published 188 times since Jan 22, 2014, and over the history we have for it it has declined 46.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3817 per ML |
|---|---|
| All-time high | $0.7147 (Nov 12, 2014) |
| All-time low | $0.3487 (Sep 18, 2024) |
| 52-week high | $0.4500 |
| 52-week low | $0.3817 |
| Median price | $0.4500 |
| Average price | $0.4845 |
| Largest weekly change | -42.5% (Nov 19, 2014) |
| Weeks tracked | 188 |
| Tracking since | Jan 22, 2014 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of MIDAZOLAM HCL 50 MG/10 ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for MIDAZOLAM HCL 50 MG/10 ML VIAL, manufactured by Hospira Inc., is $0.3817 per ML (NDC 00409259605), effective Aug 19, 2026.
How has the price of MIDAZOLAM HCL 50 MG/10 ML VIAL changed over time?
Over the history we have for it, the NADAC for MIDAZOLAM HCL 50 MG/10 ML VIAL has declined 46.6%. It has been tracked across 188 weekly CMS publications since Jan 22, 2014.
What are the highest and lowest recorded NADAC prices for MIDAZOLAM HCL 50 MG/10 ML VIAL?
Since Jan 22, 2014, the NADAC for MIDAZOLAM HCL 50 MG/10 ML VIAL has ranged from a low of $0.3487 (Sep 18, 2024) to a high of $0.7147 (Nov 12, 2014), with a median of $0.4500 per ML.
Are there cheaper alternatives to MIDAZOLAM HCL 50 MG/10 ML VIAL?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as MIDAZOLAM HCL 50 MG/10 ML VIAL in a comparable dosage form, but none are currently priced below it.
Who manufactures MIDAZOLAM HCL 50 MG/10 ML VIAL?
MIDAZOLAM HCL 50 MG/10 ML VIAL (NDC 00409259605) is labeled by Hospira Inc., and CMS classifies it as a generic product.
Is MIDAZOLAM HCL 50 MG/10 ML VIAL in shortage?
Yes — NDC 00409259605 is currently listed in FDA's drug shortage database (posted Apr 2, 2020).