This NDC is on FDA's drug shortage list (posted Nov 23, 2021)
Product Information
WATER FOR INJECTION VIAL is a generic product labeled by Hospira Inc., priced at $0.3150 per ML under NDC 00409488710. Its NADAC has been published 441 times since Nov 28, 2013.
FDA first approved this application on Oct 27, 1982. Its Orange Book therapeutic-equivalence code is AP.
Strength
1 mL/mL
Manufacturer
Hospira Inc.NDC
00409488710
Classification
Generic
Dosage Form
INJECTION
Route
INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS
Effective Date
9/23/2026
Active Ingredients
WATERApproval Type
New Drug (NDA)
FDA Application
NDA018801FDA Approved
10/27/1982
TE Code
AP
On Market Since
6/16/2005
Price Statistics
The NADAC for WATER FOR INJECTION VIAL has been published 441 times since Nov 28, 2013, and over the history we have for it it has risen 322.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3150 per ML |
|---|---|
| All-time high | $0.3206 (Apr 15, 2026) |
| All-time low | $0.0730 (Jan 22, 2014) |
| 52-week high | $0.3206 |
| 52-week low | $0.1008 |
| Median price | $0.0845 |
| Average price | $0.1069 |
| Largest weekly change | +37.0% (Nov 19, 2025) |
| Weeks tracked | 441 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 79% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Hospira Inc. manufacturer profile
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Drug market
WATER market comparison
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of WATER FOR INJECTION VIAL?
The current National Average Drug Acquisition Cost (NADAC) for WATER FOR INJECTION VIAL, manufactured by Hospira Inc., is $0.3150 per ML (NDC 00409488710), effective Sep 30, 2026.
How has the price of WATER FOR INJECTION VIAL changed over time?
Over the history we have for it, the NADAC for WATER FOR INJECTION VIAL has risen 322.5%. It has been tracked across 441 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for WATER FOR INJECTION VIAL?
Since Nov 28, 2013, the NADAC for WATER FOR INJECTION VIAL has ranged from a low of $0.0730 (Jan 22, 2014) to a high of $0.3206 (Apr 15, 2026), with a median of $0.0845 per ML.
Are there cheaper alternatives to WATER FOR INJECTION VIAL?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, WATER FOR INJECTION VIAL, is $0.0661 per ML — about 79% below WATER FOR INJECTION VIAL.
Who manufactures WATER FOR INJECTION VIAL?
WATER FOR INJECTION VIAL (NDC 00409488710) is labeled by Hospira Inc., and CMS classifies it as a generic product.
Is WATER FOR INJECTION VIAL in shortage?
Yes — NDC 00409488710 is currently listed in FDA's drug shortage database (posted Nov 23, 2021).