Product Information
SAPHRIS 5 MG TAB SUBLINGUAL is a brand product labeled by Allergan, Inc., priced at $21.1808 per EA under NDC 00456240560. Its NADAC has been published 593 times since Dec 17, 2014.
FDA first approved this application on Aug 13, 2009. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/1
Manufacturer
Allergan, Inc.NDC
00456240560
Classification
Brand
Dosage Form
TABLET
Route
SUBLINGUAL
Effective Date
8/19/2026
Active Ingredients
ASENAPINE MALEATEApproval Type
New Drug (NDA)
FDA Application
NDA022117FDA Approved
8/13/2009
TE Code
AB
On Market Since
9/30/2013
Pharmacological Classes
Price Statistics
The NADAC for SAPHRIS 5 MG TAB SUBLINGUAL has been published 593 times since Dec 17, 2014, and over the history we have for it it has risen 73.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $21.1808 per EA |
|---|---|
| All-time high | $21.2178 (Aug 12, 2026) |
| All-time low | $12.1816 (Dec 17, 2014) |
| 52-week high | $21.2178 |
| 52-week low | $20.1461 |
| Median price | $19.1429 |
| Average price | $18.3972 |
| Largest weekly change | +10.7% (Mar 18, 2015) |
| Weeks tracked | 593 |
| Tracking since | Dec 17, 2014 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Asenapine Maleate market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of SAPHRIS 5 MG TAB SUBLINGUAL?
The current National Average Drug Acquisition Cost (NADAC) for SAPHRIS 5 MG TAB SUBLINGUAL, manufactured by Allergan, Inc., is $21.1808 per EA (NDC 00456240560), effective Aug 19, 2026.
How has the price of SAPHRIS 5 MG TAB SUBLINGUAL changed over time?
Over the history we have for it, the NADAC for SAPHRIS 5 MG TAB SUBLINGUAL has risen 73.9%. It has been tracked across 593 weekly CMS publications since Dec 17, 2014.
What are the highest and lowest recorded NADAC prices for SAPHRIS 5 MG TAB SUBLINGUAL?
Since Dec 17, 2014, the NADAC for SAPHRIS 5 MG TAB SUBLINGUAL has ranged from a low of $12.1816 (Dec 17, 2014) to a high of $21.2178 (Aug 12, 2026), with a median of $19.1429 per EA.
Are there cheaper alternatives to SAPHRIS 5 MG TAB SUBLINGUAL?
No other NADAC-published product currently shares the active ingredient and strength of SAPHRIS 5 MG TAB SUBLINGUAL in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures SAPHRIS 5 MG TAB SUBLINGUAL?
SAPHRIS 5 MG TAB SUBLINGUAL (NDC 00456240560) is labeled by Allergan, Inc., and CMS classifies it as a brand product.