Product Information
DESOXIMETASONE 0.25% CREAM is a generic product labeled by Actavis Pharma, Inc., priced at $0.3937 per GM under NDC 00472047815. Its NADAC has been published 534 times since May 11, 2016.
FDA first approved this application on Sep 4, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2.5 mg/g
Manufacturer
Actavis Pharma, Inc.NDC
00472047815
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
7/22/2026
Active Ingredients
DESOXIMETASONEApproval Type
Generic (ANDA)
FDA Application
ANDA205082FDA Approved
9/4/2015
TE Code
AB
On Market Since
3/31/2016
Pharmacological Classes
Price Statistics
The NADAC for DESOXIMETASONE 0.25% CREAM has been published 534 times since May 11, 2016, and over the history we have for it it has declined 77.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3937 per GM |
|---|---|
| All-time high | $1.9357 (Aug 10, 2016) |
| All-time low | $0.3770 (Aug 20, 2025) |
| 52-week high | $0.4846 |
| 52-week low | $0.3770 |
| Median price | $1.0450 |
| Average price | $0.9796 |
| Largest weekly change | +108.7% (Mar 18, 2020) |
| Weeks tracked | 534 |
| Tracking since | May 11, 2016 |
1W
N/A
1M
0.0%
3M
-3.9%
6M
-12.6%
1Y
+4.5%
3Y
-52.3%
5Y
-63.3%
All
-77.1%
Last surveyed Jul 29, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 19% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DESOXIMETASONE 0.25% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for DESOXIMETASONE 0.25% CREAM, manufactured by Actavis Pharma, Inc., is $0.3937 per GM (NDC 00472047815), effective Jul 29, 2026.
How has the price of DESOXIMETASONE 0.25% CREAM changed over time?
Over the history we have for it, the NADAC for DESOXIMETASONE 0.25% CREAM has declined 77.1%. It has been tracked across 534 weekly CMS publications since May 11, 2016.
What are the highest and lowest recorded NADAC prices for DESOXIMETASONE 0.25% CREAM?
Since May 11, 2016, the NADAC for DESOXIMETASONE 0.25% CREAM has ranged from a low of $0.3770 (Aug 20, 2025) to a high of $1.9357 (Aug 10, 2016), with a median of $1.0450 per GM.
Are there cheaper alternatives to DESOXIMETASONE 0.25% CREAM?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DESOXIMETASONE 0.25% CREAM, is $0.3174 per GM — about 19% below DESOXIMETASONE 0.25% CREAM.
Who manufactures DESOXIMETASONE 0.25% CREAM?
DESOXIMETASONE 0.25% CREAM (NDC 00472047815) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.