Product Information

NAPROXEN SOD ER 500 MG TABLET is a generic product labeled by Teva Pharmaceuticals USA Inc., priced at $9.5851 per EA under NDC 00480095258. Its NADAC has been published 123 times since Apr 17, 2024.

FDA first approved this application on Aug 27, 2002. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the naproxen sodium market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

NAPROXEN SOD ER 500 MG TABLET

naproxen sodium
$9.5851per EA
High Outlier

Strength

500 mg/1

NDC

00480095258

Classification

Generic

Dosage Form

TABLET, FILM COATED, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

NAPROXEN SODIUM

Approval Type

Generic (ANDA)

FDA Application

ANDA075416

FDA Approved

8/27/2002

TE Code

AB

On Market Since

11/1/2022

Pharmacological Classes

Anti-Inflammatory Agents
Non-Steroidal
Cyclooxygenase Inhibitors
Nonsteroidal Anti-inflammatory Drug

Price Statistics

The NADAC for NAPROXEN SOD ER 500 MG TABLET has been published 123 times since Apr 17, 2024, and over the history we have for it it has risen 2.6%. The table below summarizes its recorded NADAC range and movement.

Current price$9.5851 per EA
All-time high$9.5930 (Aug 12, 2026)
All-time low$8.0200 (Aug 21, 2024)
52-week high$9.5930
52-week low$8.1286
Median price$8.9303
Average price$8.8489
Largest weekly change+15.1% (Nov 20, 2024)
Weeks tracked123
Tracking sinceApr 17, 2024

Price History

1W

-0.1%

1M

-0.1%

3M

+3.3%

6M

+12.7%

1Y

+3.3%

3Y

N/A

5Y

N/A

All

+2.6%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the naproxen sodium market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of NAPROXEN SOD ER 500 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for NAPROXEN SOD ER 500 MG TABLET, manufactured by Teva Pharmaceuticals USA Inc., is $9.5851 per EA (NDC 00480095258), effective Aug 19, 2026.

How has the price of NAPROXEN SOD ER 500 MG TABLET changed over time?

Over the history we have for it, the NADAC for NAPROXEN SOD ER 500 MG TABLET has risen 2.6%. It has been tracked across 123 weekly CMS publications since Apr 17, 2024.

What are the highest and lowest recorded NADAC prices for NAPROXEN SOD ER 500 MG TABLET?

Since Apr 17, 2024, the NADAC for NAPROXEN SOD ER 500 MG TABLET has ranged from a low of $8.0200 (Aug 21, 2024) to a high of $9.5930 (Aug 12, 2026), with a median of $8.9303 per EA.

Are there cheaper alternatives to NAPROXEN SOD ER 500 MG TABLET?

No other NADAC-published product currently shares the active ingredient and strength of NAPROXEN SOD ER 500 MG TABLET in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures NAPROXEN SOD ER 500 MG TABLET?

NAPROXEN SOD ER 500 MG TABLET (NDC 00480095258) is labeled by Teva Pharmaceuticals USA Inc., and CMS classifies it as a generic product.