Product Information
GUAIFENESIN-PSE ER 600-60 MG is a generic product labeled by Rugby Laboratories, priced at $0.3872 per EA under NDC 00536133321. Its NADAC has been published 227 times since Apr 20, 2022.
FDA first approved this application on Apr 28, 2020.
Strength
600; 60 mg/1; mg/1
Manufacturer
Rugby LaboratoriesNDC
00536133321
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA212542FDA Approved
4/28/2020
On Market Since
4/4/2022
Pharmacological Classes
Price Statistics
The NADAC for GUAIFENESIN-PSE ER 600-60 MG has been published 227 times since Apr 20, 2022, and over the history we have for it it has declined 16.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3872 per EA |
|---|---|
| All-time high | $0.4832 (Apr 12, 2023) |
| All-time low | $0.2640 (Jun 18, 2025) |
| 52-week high | $0.3891 |
| 52-week low | $0.2954 |
| Median price | $0.3809 |
| Average price | $0.3752 |
| Largest weekly change | +23.6% (Sep 18, 2024) |
| Weeks tracked | 227 |
| Tracking since | Apr 20, 2022 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of GUAIFENESIN-PSE ER 600-60 MG?
The current National Average Drug Acquisition Cost (NADAC) for GUAIFENESIN-PSE ER 600-60 MG, manufactured by Rugby Laboratories, is $0.3872 per EA (NDC 00536133321), effective Aug 19, 2026.
How has the price of GUAIFENESIN-PSE ER 600-60 MG changed over time?
Over the history we have for it, the NADAC for GUAIFENESIN-PSE ER 600-60 MG has declined 16.2%. It has been tracked across 227 weekly CMS publications since Apr 20, 2022.
What are the highest and lowest recorded NADAC prices for GUAIFENESIN-PSE ER 600-60 MG?
Since Apr 20, 2022, the NADAC for GUAIFENESIN-PSE ER 600-60 MG has ranged from a low of $0.2640 (Jun 18, 2025) to a high of $0.4832 (Apr 12, 2023), with a median of $0.3809 per EA.
Are there cheaper alternatives to GUAIFENESIN-PSE ER 600-60 MG?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as GUAIFENESIN-PSE ER 600-60 MG in a comparable dosage form, but none are currently priced below it.
Who manufactures GUAIFENESIN-PSE ER 600-60 MG?
GUAIFENESIN-PSE ER 600-60 MG (NDC 00536133321) is labeled by Rugby Laboratories, and CMS classifies it as a generic product.