Product Information
HYDROMORPHONE HCL ER 16 MG TAB is a generic product labeled by Padagis US LLC, priced at $11.8168 per EA under NDC 00574029501. Its NADAC has been published 299 times since Jun 17, 2015.
FDA first approved this application on Apr 6, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the hydromorphone hydrochloride market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
16 mg/1
Manufacturer
Padagis US LLCNDC
00574029501
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
HYDROMORPHONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA204278FDA Approved
4/6/2015
TE Code
AB
On Market Since
5/22/2015
Pharmacological Classes
Price Statistics
The NADAC for HYDROMORPHONE HCL ER 16 MG TAB has been published 299 times since Jun 17, 2015, and over the history we have for it it has declined 43.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $11.8168 per EA |
|---|---|
| All-time high | $21.4124 (Aug 12, 2015) |
| All-time low | $7.0776 (Jun 19, 2019) |
| 52-week high | $11.8168 |
| 52-week low | $9.5750 |
| Median price | $14.9412 |
| Average price | $14.4805 |
| Largest weekly change | -52.6% (Jun 19, 2019) |
| Weeks tracked | 299 |
| Tracking since | Jun 17, 2015 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROMORPHONE HCL ER 16 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for HYDROMORPHONE HCL ER 16 MG TAB, manufactured by Padagis US LLC, is $11.8168 per EA (NDC 00574029501), effective Aug 19, 2026.
How has the price of HYDROMORPHONE HCL ER 16 MG TAB changed over time?
Over the history we have for it, the NADAC for HYDROMORPHONE HCL ER 16 MG TAB has declined 43.2%. It has been tracked across 299 weekly CMS publications since Jun 17, 2015.
What are the highest and lowest recorded NADAC prices for HYDROMORPHONE HCL ER 16 MG TAB?
Since Jun 17, 2015, the NADAC for HYDROMORPHONE HCL ER 16 MG TAB has ranged from a low of $7.0776 (Jun 19, 2019) to a high of $21.4124 (Aug 12, 2015), with a median of $14.9412 per EA.
Are there cheaper alternatives to HYDROMORPHONE HCL ER 16 MG TAB?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as HYDROMORPHONE HCL ER 16 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures HYDROMORPHONE HCL ER 16 MG TAB?
HYDROMORPHONE HCL ER 16 MG TAB (NDC 00574029501) is labeled by Padagis US LLC, and CMS classifies it as a generic product.