Product Information

SYNJARDY 12.5-500 MG TABLET is a brand product labeled by Boehringer Ingelheim Pharmaceuticals Inc., priced at $5.6078 per EA under NDC 00597018018. Its NADAC has been published 462 times since Oct 18, 2017.

FDA first approved this application on Aug 26, 2015.

SYNJARDY 12.5-500 MG TABLET

empagliflozin and metformin hydrochloride
$5.6078per EA

Strength

12.5; 500 mg/1; mg/1

NDC

00597018018

Classification

Brand

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Approval Type

New Drug (NDA)

FDA Application

NDA206111

FDA Approved

8/26/2015

On Market Since

8/26/2015

Pharmacological Classes

Biguanide
Biguanides
Sodium-Glucose Cotransporter 2 Inhibitor
Sodium-Glucose Transporter 2 Inhibitors

Price Statistics

The NADAC for SYNJARDY 12.5-500 MG TABLET has been published 462 times since Oct 18, 2017, and over the history we have for it it has declined 18.4%. The table below summarizes its recorded NADAC range and movement.

Current price$5.6078 per EA
All-time high$10.0886 (Dec 31, 2025)
All-time low$5.5982 (May 20, 2026)
52-week high$10.0886
52-week low$5.5982
Median price$8.7728
Average price$8.5759
Largest weekly change-44.4% (Jan 7, 2026)
Weeks tracked462
Tracking sinceOct 18, 2017

Price History

1W

+0.0%

1M

+0.2%

3M

+0.2%

6M

-0.0%

1Y

-44.4%

3Y

-40.7%

5Y

-36.1%

All

-18.4%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of SYNJARDY 12.5-500 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for SYNJARDY 12.5-500 MG TABLET, manufactured by Boehringer Ingelheim Pharmaceuticals Inc., is $5.6078 per EA (NDC 00597018018), effective Aug 19, 2026.

How has the price of SYNJARDY 12.5-500 MG TABLET changed over time?

Over the history we have for it, the NADAC for SYNJARDY 12.5-500 MG TABLET has declined 18.4%. It has been tracked across 462 weekly CMS publications since Oct 18, 2017.

What are the highest and lowest recorded NADAC prices for SYNJARDY 12.5-500 MG TABLET?

Since Oct 18, 2017, the NADAC for SYNJARDY 12.5-500 MG TABLET has ranged from a low of $5.5982 (May 20, 2026) to a high of $10.0886 (Dec 31, 2025), with a median of $8.7728 per EA.

Are there cheaper alternatives to SYNJARDY 12.5-500 MG TABLET?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as SYNJARDY 12.5-500 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures SYNJARDY 12.5-500 MG TABLET?

SYNJARDY 12.5-500 MG TABLET (NDC 00597018018) is labeled by Boehringer Ingelheim Pharmaceuticals Inc., and CMS classifies it as a brand product.