Product Information
PROPRANOLOL 40 MG TABLET is a generic product labeled by Endo USA Inc., priced at $0.0766 per EA under NDC 00603548421. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Apr 14, 1986. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
40 mg/1
Manufacturer
Endo USA Inc.NDC
00603548421
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
PROPRANOLOL HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA070221FDA Approved
4/14/1986
TE Code
AB
On Market Since
6/21/2010
Pharmacological Classes
Price Statistics
The NADAC for PROPRANOLOL 40 MG TABLET has been published 671 times since Nov 28, 2013, and over the history we have for it it has risen 133.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0766 per EA |
|---|---|
| All-time high | $0.3865 (Mar 16, 2016) |
| All-time low | $0.0316 (Oct 22, 2014) |
| 52-week high | $0.0837 |
| 52-week low | $0.0764 |
| Median price | $0.1262 |
| Average price | $0.1603 |
| Largest weekly change | +356.0% (Mar 18, 2015) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Endo USA Inc. manufacturer profile
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Drug market
propranolol hydrochloride market comparison
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Therapeutic class
beta-Adrenergic Blocker class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of PROPRANOLOL 40 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for PROPRANOLOL 40 MG TABLET, manufactured by Endo USA Inc., is $0.0766 per EA (NDC 00603548421), effective Sep 30, 2026.
How has the price of PROPRANOLOL 40 MG TABLET changed over time?
Over the history we have for it, the NADAC for PROPRANOLOL 40 MG TABLET has risen 133.8%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for PROPRANOLOL 40 MG TABLET?
Since Nov 28, 2013, the NADAC for PROPRANOLOL 40 MG TABLET has ranged from a low of $0.0316 (Oct 22, 2014) to a high of $0.3865 (Mar 16, 2016), with a median of $0.1262 per EA.
Are there cheaper alternatives to PROPRANOLOL 40 MG TABLET?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PROPRANOLOL 40 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures PROPRANOLOL 40 MG TABLET?
PROPRANOLOL 40 MG TABLET (NDC 00603548421) is labeled by Endo USA Inc., and CMS classifies it as a generic product.