Propranolol Hydrochloride
87 NDCs across 13 manufacturers|81 Generic,6 Brand
Propranolol Hydrochloride is used to treat angina pectoris, esophageal and gastric varices, essential tremor, heart failure, hypertension and myocardial infarction, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved before 1982, and the first generic was approved Jul 30, 1985. FDA's Orange Book lists 70 AB-rated (therapeutically equivalent) products for this ingredient.
Propranolol Hydrochloride is available as 87 NDCs from 13 manufacturers (81 generic, 6 brand), with NADAC prices from $0.05 to $77.62 per EA — the most expensive product costs about 1,667× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Active FDA drug shortage
2 Propranolol Hydrochloride presentations are currently listed in FDA's drug shortage database (first posted Oct 31, 2023). Shortages can move NADAC prices in the following weeks.
Total NDCs
87
81G / 6B
Manufacturers
13
competing in market
Price Spread
$0.05 – $77.62
per EA, 85 of 87 NDCs
7d Activity
avg -0.7% WoW · of 87 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
ANI Pharmaceuticals, Inc. manufacturer profile
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Lead class
beta-Adrenergic Blocker class view
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Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
13 manufacturers producing PROPRANOLOL HYDROCHLORIDE(1 pricing outlier)
Frequently Asked Questions
What is Propranolol Hydrochloride used to treat?
Propranolol Hydrochloride is used to treat angina pectoris, esophageal and gastric varices, essential tremor, heart failure, hypertension and myocardial infarction, per the National Library of Medicine's MED-RT classification.
When did Propranolol Hydrochloride become available as a generic?
FDA approved the first generic Propranolol Hydrochloride (ANDA) on Jul 30, 1985. The Orange Book currently lists 70 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
Is Propranolol Hydrochloride in shortage?
Yes — FDA's drug shortage database currently lists 2 Propranolol Hydrochloride presentations with status "Current", first posted Oct 31, 2023.
How many Propranolol Hydrochloride products are on the market?
The Propranolol Hydrochloride drug market contains 87 NDCs from 13 manufacturers — 81 generic and 6 brand products.
What is the price range for Propranolol Hydrochloride?
NADAC reference prices for Propranolol Hydrochloride range from $0.0466 to $77.6159 per EA — the most expensive product costs about 1,667× the cheapest. 2 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.
Is generic Propranolol Hydrochloride cheaper than brand?
The average generic NADAC for Propranolol Hydrochloride is $0.1262 per EA, versus $71.8689 for brand-labeled products — brand versions average about 569× the generic price.
Which manufacturers make Propranolol Hydrochloride?
13 manufacturers list Propranolol Hydrochloride in NADAC. Ranked by number of NDCs, the largest are ANI Pharmaceuticals, Inc. (10), Amneal Pharmaceuticals NY LLC (9), Mylan Pharmaceuticals Inc. (9), Endo USA Inc. (9), Ipca Laboratories Limited (9).
How has the price of Propranolol Hydrochloride changed recently?
Over the past 7 days, 21 Propranolol Hydrochloride NDCs rose and 53 fell, with a market-wide average change of -0.7%.