Product Information
FENTANYL 250 MCG/5 ML VIAL is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $1.7864 per ML under NDC 00641602810. Its NADAC has been published 96 times since Dec 4, 2024.
FDA first approved this application on Jul 11, 1984. Its Orange Book therapeutic-equivalence code is AP.
The Low Outlier badge above means this manufacturer's average price in the Fentanyl Citrate market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
50 ug/mL
Manufacturer
Hikma Pharmaceuticals USA Inc.NDC
00641602810
Classification
Generic
Dosage Form
INJECTION
Route
INTRAMUSCULAR; INTRAVENOUS
Effective Date
9/23/2026
Active Ingredients
FENTANYL CITRATEApproval Type
New Drug (NDA)
FDA Application
NDA019101FDA Approved
7/11/1984
TE Code
AP
On Market Since
7/11/1984
Pharmacological Classes
Price Statistics
The NADAC for FENTANYL 250 MCG/5 ML VIAL has been published 96 times since Dec 4, 2024, and over the history we have for it it has risen 155.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.7864 per ML |
|---|---|
| All-time high | $1.7864 (Sep 30, 2026) |
| All-time low | $0.6997 (Dec 4, 2024) |
| 52-week high | $1.7864 |
| 52-week low | $1.0131 |
| Median price | $1.1582 |
| Average price | $1.0904 |
| Largest weekly change | +16.1% (Sep 17, 2025) |
| Weeks tracked | 96 |
| Tracking since | Dec 4, 2024 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 67% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Hikma Pharmaceuticals USA Inc. manufacturer profile
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Drug market
Fentanyl Citrate market comparison
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Therapeutic class
Opioid Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of FENTANYL 250 MCG/5 ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for FENTANYL 250 MCG/5 ML VIAL, manufactured by Hikma Pharmaceuticals USA Inc., is $1.7864 per ML (NDC 00641602810), effective Sep 30, 2026.
How has the price of FENTANYL 250 MCG/5 ML VIAL changed over time?
Over the history we have for it, the NADAC for FENTANYL 250 MCG/5 ML VIAL has risen 155.3%. It has been tracked across 96 weekly CMS publications since Dec 4, 2024.
What are the highest and lowest recorded NADAC prices for FENTANYL 250 MCG/5 ML VIAL?
Since Dec 4, 2024, the NADAC for FENTANYL 250 MCG/5 ML VIAL has ranged from a low of $0.6997 (Dec 4, 2024) to a high of $1.7864 (Sep 30, 2026), with a median of $1.1582 per ML.
Are there cheaper alternatives to FENTANYL 250 MCG/5 ML VIAL?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, FENTANYL 1,000 MCG/20 ML AMPUL, is $0.5981 per ML — about 67% below FENTANYL 250 MCG/5 ML VIAL.
Who manufactures FENTANYL 250 MCG/5 ML VIAL?
FENTANYL 250 MCG/5 ML VIAL (NDC 00641602810) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.