Product Information
FLUOCINONIDE-E 0.05% CREAM is a generic product labeled by Cosette Pharmaceuticals, Inc., priced at $0.6284 per GM under NDC 00713066460. Its NADAC has been published 402 times since Dec 12, 2018.
FDA first approved this application on Jun 13, 1995. Its Orange Book therapeutic-equivalence code is AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Cosette Pharmaceuticals, Inc.NDC
00713066460
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
FLUOCINONIDEApproval Type
Generic (ANDA)
FDA Application
ANDA074204FDA Approved
6/13/1995
TE Code
AB2
On Market Since
3/21/2016
Pharmacological Classes
Price Statistics
The NADAC for FLUOCINONIDE-E 0.05% CREAM has been published 402 times since Dec 12, 2018, and over the history we have for it it has declined 40.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.6284 per GM |
|---|---|
| All-time high | $1.7212 (Mar 11, 2020) |
| All-time low | $0.4955 (Feb 19, 2025) |
| 52-week high | $0.7818 |
| 52-week low | $0.5092 |
| Median price | $0.8510 |
| Average price | $0.8928 |
| Largest weekly change | +112.0% (Nov 20, 2019) |
| Weeks tracked | 402 |
| Tracking since | Dec 12, 2018 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 62% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of FLUOCINONIDE-E 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for FLUOCINONIDE-E 0.05% CREAM, manufactured by Cosette Pharmaceuticals, Inc., is $0.6284 per GM (NDC 00713066460), effective Aug 19, 2026.
How has the price of FLUOCINONIDE-E 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for FLUOCINONIDE-E 0.05% CREAM has declined 40.5%. It has been tracked across 402 weekly CMS publications since Dec 12, 2018.
What are the highest and lowest recorded NADAC prices for FLUOCINONIDE-E 0.05% CREAM?
Since Dec 12, 2018, the NADAC for FLUOCINONIDE-E 0.05% CREAM has ranged from a low of $0.4955 (Feb 19, 2025) to a high of $1.7212 (Mar 11, 2020), with a median of $0.8510 per GM.
Are there cheaper alternatives to FLUOCINONIDE-E 0.05% CREAM?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, FLUOCINONIDE 0.05% CREAM, is $0.2402 per GM — about 62% below FLUOCINONIDE-E 0.05% CREAM.
Who manufactures FLUOCINONIDE-E 0.05% CREAM?
FLUOCINONIDE-E 0.05% CREAM (NDC 00713066460) is labeled by Cosette Pharmaceuticals, Inc., and CMS classifies it as a generic product.