Product Information
FLUOCINONIDE 0.05% CREAM is a generic product labeled by Encube Ethicals, Inc., priced at $0.2469 per GM under NDC 21922006407. Its NADAC has been published 25 times since Jan 7, 2026.
Strength
.5 mg/g
Manufacturer
Encube Ethicals, Inc.NDC
21922006407
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
FLUOCINONIDEApproval Type
Generic (ANDA)
FDA Application
ANDA211410On Market Since
2/25/2025
Pharmacological Classes
Price Statistics
The NADAC for FLUOCINONIDE 0.05% CREAM has been published 25 times since Jan 7, 2026, and over the history we have for it it has declined 23.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2469 per GM |
|---|---|
| All-time high | $0.3224 (Feb 11, 2026) |
| All-time low | $0.2469 (Jun 17, 2026) |
| 52-week high | $0.3224 |
| 52-week low | $0.2469 |
| Median price | $0.2967 |
| Average price | $0.2943 |
| Largest weekly change | -8.8% (May 20, 2026) |
| Weeks tracked | 25 |
| Tracking since | Jan 7, 2026 |
Generic Alternatives
The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 16% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of FLUOCINONIDE 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for FLUOCINONIDE 0.05% CREAM, manufactured by Encube Ethicals, Inc., is $0.2469 per GM (NDC 21922006407), effective Jun 24, 2026.
How has the price of FLUOCINONIDE 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for FLUOCINONIDE 0.05% CREAM has declined 23.0%. It has been tracked across 25 weekly CMS publications since Jan 7, 2026.
What are the highest and lowest recorded NADAC prices for FLUOCINONIDE 0.05% CREAM?
Since Jan 7, 2026, the NADAC for FLUOCINONIDE 0.05% CREAM has ranged from a low of $0.2469 (Jun 17, 2026) to a high of $0.3224 (Feb 11, 2026), with a median of $0.2967 per GM.
Are there cheaper alternatives to FLUOCINONIDE 0.05% CREAM?
Yes. 5 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, FLUOCINONIDE 0.05% OINTMENT, is $0.2084 per GM — about 16% below FLUOCINONIDE 0.05% CREAM.
Who manufactures FLUOCINONIDE 0.05% CREAM?
FLUOCINONIDE 0.05% CREAM (NDC 21922006407) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.
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