Product Information

AMBIEN CR 12.5 MG TABLET is a brand product labeled by Cosette Pharmaceuticals, Inc., priced at $22.5920 per EA under NDC 00713552101. Its NADAC has been published 63 times since Jun 11, 2025.

FDA first approved this application on Sep 2, 2005. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the zolpidem tartrate market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

AMBIEN CR 12.5 MG TABLET

zolpidem tartrate
$22.5920per EA
High Outlier
DEA Schedule CIV

Strength

12.5 mg/1

NDC

00713552101

Classification

Brand

Dosage Form

TABLET, COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

ZOLPIDEM TARTRATE

Approval Type

New Drug (NDA)

FDA Application

NDA021774

FDA Approved

9/2/2005

TE Code

AB

On Market Since

2/7/2025

Pharmacological Classes

Central Nervous System Depression
GABA A Receptor Positive Modulators
gamma-Aminobutyric Acid A Receptor Positive Modulator

Price Statistics

The NADAC for AMBIEN CR 12.5 MG TABLET has been published 63 times since Jun 11, 2025, and over the history we have for it it has risen 9.5%. The table below summarizes its recorded NADAC range and movement.

Current price$22.5920 per EA
All-time high$22.5920 (Aug 19, 2026)
All-time low$20.5394 (Dec 17, 2025)
52-week high$22.5920
52-week low$20.5394
Median price$20.6308
Average price$21.4503
Largest weekly change+9.9% (Feb 18, 2026)
Weeks tracked63
Tracking sinceJun 11, 2025

Price History

1W

+0.1%

1M

+0.1%

3M

+0.1%

6M

+0.1%

1Y

+9.5%

3Y

N/A

5Y

N/A

All

+9.5%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 99%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of AMBIEN CR 12.5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for AMBIEN CR 12.5 MG TABLET, manufactured by Cosette Pharmaceuticals, Inc., is $22.5920 per EA (NDC 00713552101), effective Aug 19, 2026.

How has the price of AMBIEN CR 12.5 MG TABLET changed over time?

Over the history we have for it, the NADAC for AMBIEN CR 12.5 MG TABLET has risen 9.5%. It has been tracked across 63 weekly CMS publications since Jun 11, 2025.

What are the highest and lowest recorded NADAC prices for AMBIEN CR 12.5 MG TABLET?

Since Jun 11, 2025, the NADAC for AMBIEN CR 12.5 MG TABLET has ranged from a low of $20.5394 (Dec 17, 2025) to a high of $22.5920 (Aug 19, 2026), with a median of $20.6308 per EA.

Are there cheaper alternatives to AMBIEN CR 12.5 MG TABLET?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ZOLPIDEM TART ER 12.5 MG TAB, is $0.1130 per EA — about 99% below AMBIEN CR 12.5 MG TABLET.

Who manufactures AMBIEN CR 12.5 MG TABLET?

AMBIEN CR 12.5 MG TABLET (NDC 00713552101) is labeled by Cosette Pharmaceuticals, Inc., and CMS classifies it as a brand product.