Product Information

BUTALBITAL-ASPIRIN-CAFFEINE 50-325-40 MG CAPSULE is a generic product labeled by Sandoz Inc., priced at $0.9750 per EA under NDC 00781227001. Its NADAC has been published 86 times since Nov 6, 2024.

BUTALBITAL-ASPIRIN-CAFFEINE 50-325-40 MG CAPSULE

Butalbital, aspirin, and caffeine
$0.9750per EA
DEA Schedule CIII

Strength

325; 50; 40 mg/1; mg/1; mg/1

Manufacturer

Sandoz Inc.

NDC

00781227001

Classification

Generic

Dosage Form

CAPSULE

Route

ORAL

Last Updated

6/17/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA086996

On Market Since

9/3/2024

Pharmacological Classes

Anti-Inflammatory Agents
Non-Steroidal
Barbiturate
Barbiturates
Central Nervous System Stimulant
Central Nervous System Stimulation
Cyclooxygenase Inhibitors
Decreased Platelet Aggregation
Decreased Prostaglandin Production
Methylxanthine
Nonsteroidal Anti-inflammatory Drug
Platelet Aggregation Inhibitor
Xanthines

Price Statistics

The NADAC for BUTALBITAL-ASPIRIN-CAFFEINE 50-325-40 MG CAPSULE has been published 86 times since Nov 6, 2024, and over the history we have for it it has risen 30.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.9750 per EA
All-time high$1.0486 (Sep 10, 2025)
All-time low$0.3623 (Nov 20, 2024)
52-week high$1.0486
52-week low$0.9704
Median price$0.9797
Average price$0.9100
Largest weekly change+59.7% (Dec 18, 2024)
Weeks tracked86
Tracking sinceNov 6, 2024

Price History

1W

0.0%

1M

-0.3%

3M

-0.4%

6M

-0.8%

1Y

-4.0%

3Y

N/A

5Y

N/A

All

+30.1%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUTALBITAL-ASPIRIN-CAFFEINE 50-325-40 MG CAPSULE?

The current National Average Drug Acquisition Cost (NADAC) for BUTALBITAL-ASPIRIN-CAFFEINE 50-325-40 MG CAPSULE, manufactured by Sandoz Inc., is $0.9750 per EA (NDC 00781227001), effective Jun 24, 2026.

How has the price of BUTALBITAL-ASPIRIN-CAFFEINE 50-325-40 MG CAPSULE changed over time?

Over the history we have for it, the NADAC for BUTALBITAL-ASPIRIN-CAFFEINE 50-325-40 MG CAPSULE has risen 30.1%. It has been tracked across 86 weekly CMS publications since Nov 6, 2024.

What are the highest and lowest recorded NADAC prices for BUTALBITAL-ASPIRIN-CAFFEINE 50-325-40 MG CAPSULE?

Since Nov 6, 2024, the NADAC for BUTALBITAL-ASPIRIN-CAFFEINE 50-325-40 MG CAPSULE has ranged from a low of $0.3623 (Nov 20, 2024) to a high of $1.0486 (Sep 10, 2025), with a median of $0.9797 per EA.

Are there cheaper alternatives to BUTALBITAL-ASPIRIN-CAFFEINE 50-325-40 MG CAPSULE?

1 NADAC-published product shares the same active ingredient, strength, and dosage form as BUTALBITAL-ASPIRIN-CAFFEINE 50-325-40 MG CAPSULE, but none are currently priced below it.

Who manufactures BUTALBITAL-ASPIRIN-CAFFEINE 50-325-40 MG CAPSULE?

BUTALBITAL-ASPIRIN-CAFFEINE 50-325-40 MG CAPSULE (NDC 00781227001) is labeled by Sandoz Inc., and CMS classifies it as a generic product.