Product Information
CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB is a generic product labeled by Sandoz Inc., priced at $0.5791 per EA under NDC 00781561301. Its NADAC has been published 360 times since Aug 20, 2014.
FDA first approved this application on Jun 11, 2003. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
12.5; 200; 50 mg/1; mg/1; mg/1
Manufacturer
Sandoz Inc.NDC
00781561301
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
CARBIDOPA; ENTACAPONE; LEVODOPAApproval Type
Authorized Generic (NDA)
FDA Application
NDA021485FDA Approved
6/11/2003
TE Code
AB
On Market Since
6/18/2014
Pharmacological Classes
Price Statistics
The NADAC for CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB has been published 360 times since Aug 20, 2014, and over the history we have for it it has declined 76.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5791 per EA |
|---|---|
| All-time high | $2.8209 (Mar 11, 2015) |
| All-time low | $0.5791 (Sep 23, 2026) |
| 52-week high | $1.1038 |
| 52-week low | $0.5791 |
| Median price | $1.0951 |
| Average price | $1.4872 |
| Largest weekly change | -50.5% (Oct 17, 2018) |
| Weeks tracked | 360 |
| Tracking since | Aug 20, 2014 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Carbidopa, Levodopa, and Entacapone market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Sandoz Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Carbidopa, Levodopa, and Entacapone market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Aromatic Amino Acid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB, manufactured by Sandoz Inc., is $0.5791 per EA (NDC 00781561301), effective Sep 30, 2026.
How has the price of CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB changed over time?
Over the history we have for it, the NADAC for CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB has declined 76.1%. It has been tracked across 360 weekly CMS publications since Aug 20, 2014.
What are the highest and lowest recorded NADAC prices for CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB?
Since Aug 20, 2014, the NADAC for CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB has ranged from a low of $0.5791 (Sep 23, 2026) to a high of $2.8209 (Mar 11, 2015), with a median of $1.0951 per EA.
Are there cheaper alternatives to CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB?
No other NADAC-published product currently shares the active ingredient and strength of CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB?
CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB (NDC 00781561301) is labeled by Sandoz Inc., and CMS classifies it as a generic product.