Product Information
PIPERACIL-TAZOBACT 3.375 GM VL is a generic product labeled by Sandoz Inc., priced at $3.6157 per EA under NDC 00781921395. Its NADAC has been published 72 times since Jul 17, 2024.
FDA first approved this application on Oct 21, 2010. Its Orange Book therapeutic-equivalence code is AP.
The High Outlier badge above means this manufacturer's average price in the Piperacillin and Tazobactam market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
3; .375 g/15mL; g/15mL
Manufacturer
Sandoz Inc.NDC
00781921395
Classification
Generic
Dosage Form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Route
INTRAVENOUS; PARENTERAL
Effective Date
11/19/2025
Active Ingredients
PIPERACILLIN SODIUM; TAZOBACTAM SODIUMApproval Type
Generic (ANDA)
FDA Application
ANDA065362FDA Approved
10/21/2010
TE Code
AP
On Market Since
10/21/2010
Pharmacological Classes
Price Statistics
The NADAC for PIPERACIL-TAZOBACT 3.375 GM VL has been published 72 times since Jul 17, 2024, and over the history we have for it it has declined 20.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $3.6157 per EA |
|---|---|
| All-time high | $4.5612 (Oct 16, 2024) |
| All-time low | $2.8072 (May 21, 2025) |
| 52-week high | $3.6157 |
| 52-week low | $3.2422 |
| Median price | $3.5314 |
| Average price | $3.5502 |
| Largest weekly change | -17.8% (Oct 23, 2024) |
| Weeks tracked | 72 |
| Tracking since | Jul 17, 2024 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
+11.5%
3Y
N/A
5Y
N/A
All
-20.7%
Last surveyed Nov 26, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of PIPERACIL-TAZOBACT 3.375 GM VL?
The current National Average Drug Acquisition Cost (NADAC) for PIPERACIL-TAZOBACT 3.375 GM VL, manufactured by Sandoz Inc., is $3.6157 per EA (NDC 00781921395), effective Nov 26, 2025.
How has the price of PIPERACIL-TAZOBACT 3.375 GM VL changed over time?
Over the history we have for it, the NADAC for PIPERACIL-TAZOBACT 3.375 GM VL has declined 20.7%. It has been tracked across 72 weekly CMS publications since Jul 17, 2024.
What are the highest and lowest recorded NADAC prices for PIPERACIL-TAZOBACT 3.375 GM VL?
Since Jul 17, 2024, the NADAC for PIPERACIL-TAZOBACT 3.375 GM VL has ranged from a low of $2.8072 (May 21, 2025) to a high of $4.5612 (Oct 16, 2024), with a median of $3.5314 per EA.
Are there cheaper alternatives to PIPERACIL-TAZOBACT 3.375 GM VL?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, PIPERACIL-TAZOBACT 3.375 GM VL, is $3.4926 per EA — about 3% below PIPERACIL-TAZOBACT 3.375 GM VL.
Who manufactures PIPERACIL-TAZOBACT 3.375 GM VL?
PIPERACIL-TAZOBACT 3.375 GM VL (NDC 00781921395) is labeled by Sandoz Inc., and CMS classifies it as a generic product.