Product Information
PIPERACIL-TAZOBACT 3.375 GM VL is a generic product labeled by Sandoz Inc., priced at $3.6157 per EA under NDC 00781921395. Its NADAC has been published 72 times since Jul 17, 2024.
FDA first approved this application on Oct 21, 2010. Its Orange Book therapeutic-equivalence code is AP.
The High Outlier badge above means this manufacturer's average price in the Piperacillin and Tazobactam market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
3; .375 g/15mL; g/15mL
Manufacturer
Sandoz Inc.NDC
00781921395
Classification
Generic
Dosage Form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Route
INTRAVENOUS; PARENTERAL
Effective Date
11/19/2025
Active Ingredients
PIPERACILLIN SODIUM; TAZOBACTAM SODIUMApproval Type
Generic (ANDA)
FDA Application
ANDA065362FDA Approved
10/21/2010
TE Code
AP
On Market Since
10/21/2010
Pharmacological Classes
Price Statistics
The NADAC for PIPERACIL-TAZOBACT 3.375 GM VL has been published 72 times since Jul 17, 2024, and over the history we have for it it has declined 20.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $3.6157 per EA |
|---|---|
| All-time high | $4.5612 (Oct 16, 2024) |
| All-time low | $2.8072 (May 21, 2025) |
| 52-week high | $3.6157 |
| 52-week low | $3.5731 |
| Median price | $3.5314 |
| Average price | $3.5502 |
| Largest weekly change | -17.8% (Oct 23, 2024) |
| Weeks tracked | 72 |
| Tracking since | Jul 17, 2024 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
+1.2%
3Y
N/A
5Y
N/A
All
-20.7%
Last surveyed Nov 26, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Sandoz Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Piperacillin and Tazobactam market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Penicillin-class Antibacterial class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of PIPERACIL-TAZOBACT 3.375 GM VL?
The current National Average Drug Acquisition Cost (NADAC) for PIPERACIL-TAZOBACT 3.375 GM VL, manufactured by Sandoz Inc., is $3.6157 per EA (NDC 00781921395), effective Nov 26, 2025.
How has the price of PIPERACIL-TAZOBACT 3.375 GM VL changed over time?
Over the history we have for it, the NADAC for PIPERACIL-TAZOBACT 3.375 GM VL has declined 20.7%. It has been tracked across 72 weekly CMS publications since Jul 17, 2024.
What are the highest and lowest recorded NADAC prices for PIPERACIL-TAZOBACT 3.375 GM VL?
Since Jul 17, 2024, the NADAC for PIPERACIL-TAZOBACT 3.375 GM VL has ranged from a low of $2.8072 (May 21, 2025) to a high of $4.5612 (Oct 16, 2024), with a median of $3.5314 per EA.
Are there cheaper alternatives to PIPERACIL-TAZOBACT 3.375 GM VL?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, PIPERACIL-TAZOBACT 3.375 GM VL, is $3.4926 per EA — about 3% below PIPERACIL-TAZOBACT 3.375 GM VL.
Who manufactures PIPERACIL-TAZOBACT 3.375 GM VL?
PIPERACIL-TAZOBACT 3.375 GM VL (NDC 00781921395) is labeled by Sandoz Inc., and CMS classifies it as a generic product.