Product Information
PROPAFENONE HCL ER 425 MG CAP is a generic product labeled by Upsher-Smith Laboratories LLC, priced at $0.5650 per EA under NDC 00832074260. Its NADAC has been published 141 times since Nov 11, 2020.
FDA first approved this application on Jun 25, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
425 mg/1
Manufacturer
Upsher-Smith Laboratories LLCNDC
00832074260
Classification
Generic
Dosage Form
CAPSULE, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
PROPAFENONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA212744FDA Approved
6/25/2020
TE Code
AB
On Market Since
6/25/2020
Pharmacological Classes
Price Statistics
The NADAC for PROPAFENONE HCL ER 425 MG CAP has been published 141 times since Nov 11, 2020, and over the history we have for it it has declined 84.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5650 per EA |
|---|---|
| All-time high | $3.6869 (Mar 10, 2021) |
| All-time low | $0.5637 (Jul 22, 2026) |
| 52-week high | $1.1142 |
| 52-week low | $0.5637 |
| Median price | $1.0121 |
| Average price | $1.3181 |
| Largest weekly change | -62.1% (Apr 17, 2024) |
| Weeks tracked | 141 |
| Tracking since | Nov 11, 2020 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of PROPAFENONE HCL ER 425 MG CAP?
The current National Average Drug Acquisition Cost (NADAC) for PROPAFENONE HCL ER 425 MG CAP, manufactured by Upsher-Smith Laboratories LLC, is $0.5650 per EA (NDC 00832074260), effective Aug 19, 2026.
How has the price of PROPAFENONE HCL ER 425 MG CAP changed over time?
Over the history we have for it, the NADAC for PROPAFENONE HCL ER 425 MG CAP has declined 84.7%. It has been tracked across 141 weekly CMS publications since Nov 11, 2020.
What are the highest and lowest recorded NADAC prices for PROPAFENONE HCL ER 425 MG CAP?
Since Nov 11, 2020, the NADAC for PROPAFENONE HCL ER 425 MG CAP has ranged from a low of $0.5637 (Jul 22, 2026) to a high of $3.6869 (Mar 10, 2021), with a median of $1.0121 per EA.
Are there cheaper alternatives to PROPAFENONE HCL ER 425 MG CAP?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as PROPAFENONE HCL ER 425 MG CAP in a comparable dosage form, but none are currently priced below it.
Who manufactures PROPAFENONE HCL ER 425 MG CAP?
PROPAFENONE HCL ER 425 MG CAP (NDC 00832074260) is labeled by Upsher-Smith Laboratories LLC, and CMS classifies it as a generic product.