Product Information

OPVEE 2.7 MG NASAL SPRAY is a brand product labeled by Indivior Inc., priced at $46.7887 per EA under NDC 12496000302. Its NADAC has been published 45 times since Aug 20, 2025.

OPVEE 2.7 MG NASAL SPRAY

nalmefene hydrochloride
$46.7887per EA

Strength

2.7 mg/100uL

Manufacturer

Indivior Inc.

NDC

12496000302

Classification

Brand

Dosage Form

SPRAY

Route

NASAL

Last Updated

6/17/2026

Active Ingredients

NALMEFENE HYDROCHLORIDE

Approval Type

New Drug (NDA)

FDA Application

NDA217470

On Market Since

10/2/2023

Pharmacological Classes

Opioid Antagonist
Opioid Antagonists

Price Statistics

The NADAC for OPVEE 2.7 MG NASAL SPRAY has been published 45 times since Aug 20, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.

Current price$46.7887 per EA
All-time high$46.8392 (Apr 15, 2026)
All-time low$46.7321 (Oct 22, 2025)
52-week high$46.8392
52-week low$46.7321
Median price$46.7839
Average price$46.7902
Largest weekly change-0.2% (Oct 22, 2025)
Weeks tracked45
Tracking sinceAug 20, 2025

Price History

1W

0.0%

1M

+0.0%

3M

-0.1%

6M

-0.0%

1Y

N/A

3Y

N/A

5Y

N/A

All

-0.1%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient, strength, and dosage form. Compare the broader picture on the nalmefene hydrochloride market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient, strength, and dosage form.

Frequently asked questions

What is the NADAC price of OPVEE 2.7 MG NASAL SPRAY?

The current National Average Drug Acquisition Cost (NADAC) for OPVEE 2.7 MG NASAL SPRAY, manufactured by Indivior Inc., is $46.7887 per EA (NDC 12496000302), effective Jun 24, 2026.

How has the price of OPVEE 2.7 MG NASAL SPRAY changed over time?

Over the history we have for it, the NADAC for OPVEE 2.7 MG NASAL SPRAY has held within roughly two percent of its current level. It has been tracked across 45 weekly CMS publications since Aug 20, 2025.

What are the highest and lowest recorded NADAC prices for OPVEE 2.7 MG NASAL SPRAY?

Since Aug 20, 2025, the NADAC for OPVEE 2.7 MG NASAL SPRAY has ranged from a low of $46.7321 (Oct 22, 2025) to a high of $46.8392 (Apr 15, 2026), with a median of $46.7839 per EA.

Are there cheaper alternatives to OPVEE 2.7 MG NASAL SPRAY?

No other NADAC-published product currently shares the active ingredient, strength, and dosage form of OPVEE 2.7 MG NASAL SPRAY, so no direct lower-cost alternative is listed.

Who manufactures OPVEE 2.7 MG NASAL SPRAY?

OPVEE 2.7 MG NASAL SPRAY (NDC 12496000302) is labeled by Indivior Inc., and CMS classifies it as a brand product.