Product Information
HYDROCORTISONE VAL 0.2% CREAM is a generic product labeled by Encube Ethicals, Inc., priced at $0.3292 per GM under NDC 21922000706. Its NADAC has been published 154 times since Dec 14, 2022.
FDA first approved this application on Nov 4, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2 mg/g
Manufacturer
Encube Ethicals, Inc.NDC
21922000706
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
11/19/2025
Active Ingredients
HYDROCORTISONE VALERATEApproval Type
Generic (ANDA)
FDA Application
ANDA211047FDA Approved
11/4/2021
TE Code
AB
On Market Since
12/31/2022
Pharmacological Classes
Price Statistics
The NADAC for HYDROCORTISONE VAL 0.2% CREAM has been published 154 times since Dec 14, 2022, and over the history we have for it it has declined 21.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3292 per GM |
|---|---|
| All-time high | $0.6651 (Jul 12, 2023) |
| All-time low | $0.2120 (Jul 17, 2024) |
| 52-week high | $0.3532 |
| 52-week low | $0.3214 |
| Median price | $0.3052 |
| Average price | $0.3400 |
| Largest weekly change | -54.1% (Jul 19, 2023) |
| Weeks tracked | 154 |
| Tracking since | Dec 14, 2022 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
+2.4%
3Y
+7.9%
5Y
N/A
All
-21.5%
Last surveyed Nov 19, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 20% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROCORTISONE VAL 0.2% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCORTISONE VAL 0.2% CREAM, manufactured by Encube Ethicals, Inc., is $0.3292 per GM (NDC 21922000706), effective Nov 19, 2025.
How has the price of HYDROCORTISONE VAL 0.2% CREAM changed over time?
Over the history we have for it, the NADAC for HYDROCORTISONE VAL 0.2% CREAM has declined 21.5%. It has been tracked across 154 weekly CMS publications since Dec 14, 2022.
What are the highest and lowest recorded NADAC prices for HYDROCORTISONE VAL 0.2% CREAM?
Since Dec 14, 2022, the NADAC for HYDROCORTISONE VAL 0.2% CREAM has ranged from a low of $0.2120 (Jul 17, 2024) to a high of $0.6651 (Jul 12, 2023), with a median of $0.3052 per GM.
Are there cheaper alternatives to HYDROCORTISONE VAL 0.2% CREAM?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROCORTISONE VAL 0.2% CREAM, is $0.2627 per GM — about 20% below HYDROCORTISONE VAL 0.2% CREAM.
Who manufactures HYDROCORTISONE VAL 0.2% CREAM?
HYDROCORTISONE VAL 0.2% CREAM (NDC 21922000706) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.