Product Information
METRONIDAZOLE VAGINAL 0.75% GL is a generic product labeled by Encube Ethicals, Inc., priced at $0.1406 per GM under NDC 21922003923. Its NADAC has been published 134 times since Mar 13, 2024.
FDA first approved this application on Jun 16, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
7.5 mg/g
Manufacturer
Encube Ethicals, Inc.NDC
21922003923
Classification
Generic
Dosage Form
GEL
Route
VAGINAL
Effective Date
9/23/2026
Active Ingredients
METRONIDAZOLEApproval Type
Generic (ANDA)
FDA Application
ANDA215610FDA Approved
6/16/2023
TE Code
AB
On Market Since
6/17/2023
Pharmacological Classes
Price Statistics
The NADAC for METRONIDAZOLE VAGINAL 0.75% GL has been published 134 times since Mar 13, 2024, and over the history we have for it it has declined 60.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1406 per GM |
|---|---|
| All-time high | $0.4140 (Apr 10, 2024) |
| All-time low | $0.1405 (Jul 22, 2026) |
| 52-week high | $0.1847 |
| 52-week low | $0.1405 |
| Median price | $0.1890 |
| Average price | $0.2097 |
| Largest weekly change | -40.7% (Nov 20, 2024) |
| Weeks tracked | 134 |
| Tracking since | Mar 13, 2024 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Encube Ethicals, Inc. manufacturer profile
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Drug market
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Therapeutic class
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METRONIDAZOLE VAGINAL 0.75% GL?
The current National Average Drug Acquisition Cost (NADAC) for METRONIDAZOLE VAGINAL 0.75% GL, manufactured by Encube Ethicals, Inc., is $0.1406 per GM (NDC 21922003923), effective Sep 30, 2026.
How has the price of METRONIDAZOLE VAGINAL 0.75% GL changed over time?
Over the history we have for it, the NADAC for METRONIDAZOLE VAGINAL 0.75% GL has declined 60.3%. It has been tracked across 134 weekly CMS publications since Mar 13, 2024.
What are the highest and lowest recorded NADAC prices for METRONIDAZOLE VAGINAL 0.75% GL?
Since Mar 13, 2024, the NADAC for METRONIDAZOLE VAGINAL 0.75% GL has ranged from a low of $0.1405 (Jul 22, 2026) to a high of $0.4140 (Apr 10, 2024), with a median of $0.1890 per GM.
Are there cheaper alternatives to METRONIDAZOLE VAGINAL 0.75% GL?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as METRONIDAZOLE VAGINAL 0.75% GL in a comparable dosage form, but none are currently priced below it.
Who manufactures METRONIDAZOLE VAGINAL 0.75% GL?
METRONIDAZOLE VAGINAL 0.75% GL (NDC 21922003923) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.