Product Information

SERTRALINE HCL 25 MG TABLET is a generic product labeled by Heritage Pharmaceuticals Inc., priced at $0.0282 per EA under NDC 23155075705. Its NADAC has been published 128 times since Mar 13, 2024.

FDA first approved this application on Aug 11, 2006. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

SERTRALINE HCL 25 MG TABLET

Sertraline
$0.0282per EA

Strength

25 mg/1

NDC

23155075705

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

SERTRALINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA076465

FDA Approved

8/11/2006

TE Code

AB

On Market Since

2/23/2023

Pharmacological Classes

Cytochrome P450 2D6 Inhibitors
Serotonin Reuptake Inhibitor
Serotonin Uptake Inhibitors

Price Statistics

The NADAC for SERTRALINE HCL 25 MG TABLET has been published 128 times since Mar 13, 2024, and over the history we have for it it has declined 11.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0282 per EA
All-time high$0.0398 (Sep 11, 2024)
All-time low$0.0282 (Aug 19, 2026)
52-week high$0.0336
52-week low$0.0282
Median price$0.0323
Average price$0.0324
Largest weekly change-24.8% (Nov 20, 2024)
Weeks tracked128
Tracking sinceMar 13, 2024

Price History

1W

-1.3%

1M

-1.3%

3M

-5.4%

6M

-11.9%

1Y

-14.8%

3Y

N/A

5Y

N/A

All

-11.4%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of SERTRALINE HCL 25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for SERTRALINE HCL 25 MG TABLET, manufactured by Heritage Pharmaceuticals Inc., is $0.0282 per EA (NDC 23155075705), effective Aug 19, 2026.

How has the price of SERTRALINE HCL 25 MG TABLET changed over time?

Over the history we have for it, the NADAC for SERTRALINE HCL 25 MG TABLET has declined 11.4%. It has been tracked across 128 weekly CMS publications since Mar 13, 2024.

What are the highest and lowest recorded NADAC prices for SERTRALINE HCL 25 MG TABLET?

Since Mar 13, 2024, the NADAC for SERTRALINE HCL 25 MG TABLET has ranged from a low of $0.0282 (Aug 19, 2026) to a high of $0.0398 (Sep 11, 2024), with a median of $0.0323 per EA.

Are there cheaper alternatives to SERTRALINE HCL 25 MG TABLET?

3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as SERTRALINE HCL 25 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures SERTRALINE HCL 25 MG TABLET?

SERTRALINE HCL 25 MG TABLET (NDC 23155075705) is labeled by Heritage Pharmaceuticals Inc., and CMS classifies it as a generic product.