Product Information

ZYLET EYE DROPS is a brand product labeled by Bausch & Lomb Incorporated, priced at $64.3922 per ML under NDC 24208035805. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Dec 14, 2004. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ZYLET EYE DROPS

loteprednol etabonate and tobramycin
$64.3922per ML

Strength

5; 3 mg/mL; mg/mL

NDC

24208035805

Classification

Brand

Dosage Form

SUSPENSION/ DROPS

Route

OPHTHALMIC

Effective Date

8/19/2026

Approval Type

New Drug (NDA)

FDA Application

NDA050804

FDA Approved

12/14/2004

TE Code

AB

On Market Since

12/14/2004

Pharmacological Classes

Aminoglycoside Antibacterial
Aminoglycosides
Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for ZYLET EYE DROPS has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 111.9%. The table below summarizes its recorded NADAC range and movement.

Current price$64.3922 per ML
All-time high$64.6612 (Aug 13, 2025)
All-time low$30.3878 (Nov 28, 2013)
52-week high$64.6046
52-week low$64.3922
Median price$50.3293
Average price$49.7916
Largest weekly change+10.0% (Jan 14, 2015)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

-0.1%

1M

-0.2%

3M

-0.2%

6M

-0.2%

1Y

-0.3%

3Y

+7.8%

5Y

+21.1%

All

+111.9%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of ZYLET EYE DROPS?

The current National Average Drug Acquisition Cost (NADAC) for ZYLET EYE DROPS, manufactured by Bausch & Lomb Incorporated, is $64.3922 per ML (NDC 24208035805), effective Aug 19, 2026.

How has the price of ZYLET EYE DROPS changed over time?

Over the history we have for it, the NADAC for ZYLET EYE DROPS has risen 111.9%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for ZYLET EYE DROPS?

Since Nov 28, 2013, the NADAC for ZYLET EYE DROPS has ranged from a low of $30.3878 (Nov 28, 2013) to a high of $64.6612 (Aug 13, 2025), with a median of $50.3293 per ML.

Are there cheaper alternatives to ZYLET EYE DROPS?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as ZYLET EYE DROPS in a comparable dosage form, but none are currently priced below it.

Who manufactures ZYLET EYE DROPS?

ZYLET EYE DROPS (NDC 24208035805) is labeled by Bausch & Lomb Incorporated, and CMS classifies it as a brand product.