Product Information

DILTIAZEM 24H ER(CD) 300 MG CP is a generic product labeled by Upsher-Smith Laboratories LLC, priced at $0.3091 per EA under NDC 24979002906. Its NADAC has been published 307 times since Jul 3, 2019.

FDA first approved this application on Aug 30, 2018. Its Orange Book therapeutic-equivalence code is AB3 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

DILTIAZEM 24H ER(CD) 300 MG CP

Diltiazem hydrochloride
$0.3091per EA

Strength

300 mg/1

NDC

24979002906

Classification

Generic

Dosage Form

CAPSULE, EXTENDED RELEASE

Route

ORAL

Effective Date

4/23/2025

Active Ingredients

DILTIAZEM HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA205231

FDA Approved

8/30/2018

TE Code

AB3

On Market Since

10/1/2018

Pharmacological Classes

Calcium Channel Antagonists
Calcium Channel Blocker
Cytochrome P450 3A4 Inhibitors

Price Statistics

The NADAC for DILTIAZEM 24H ER(CD) 300 MG CP has been published 307 times since Jul 3, 2019, and over the history we have for it it has declined 34.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3091 per EA
All-time high$0.5656 (Aug 14, 2019)
All-time low$0.2613 (Apr 19, 2023)
Median price$0.3699
Average price$0.3879
Largest weekly change+35.3% (Aug 21, 2024)
Weeks tracked307
Tracking sinceJul 3, 2019

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

N/A

3Y

+5.4%

5Y

-22.1%

All

-34.4%

Last surveyed May 14, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DILTIAZEM 24H ER(CD) 300 MG CP?

The current National Average Drug Acquisition Cost (NADAC) for DILTIAZEM 24H ER(CD) 300 MG CP, manufactured by Upsher-Smith Laboratories LLC, is $0.3091 per EA (NDC 24979002906), effective May 14, 2025.

How has the price of DILTIAZEM 24H ER(CD) 300 MG CP changed over time?

Over the history we have for it, the NADAC for DILTIAZEM 24H ER(CD) 300 MG CP has declined 34.4%. It has been tracked across 307 weekly CMS publications since Jul 3, 2019.

What are the highest and lowest recorded NADAC prices for DILTIAZEM 24H ER(CD) 300 MG CP?

Since Jul 3, 2019, the NADAC for DILTIAZEM 24H ER(CD) 300 MG CP has ranged from a low of $0.2613 (Apr 19, 2023) to a high of $0.5656 (Aug 14, 2019), with a median of $0.3699 per EA.

Are there cheaper alternatives to DILTIAZEM 24H ER(CD) 300 MG CP?

Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DILTIAZEM 24H ER(CD) 300 MG CP, is $0.3005 per EA — about 3% below DILTIAZEM 24H ER(CD) 300 MG CP.

Who manufactures DILTIAZEM 24H ER(CD) 300 MG CP?

DILTIAZEM 24H ER(CD) 300 MG CP (NDC 24979002906) is labeled by Upsher-Smith Laboratories LLC, and CMS classifies it as a generic product.