Product Information
GUANFACINE HCL ER 1 MG TABLET is a generic product labeled by Upsher-Smith Laboratories LLC, priced at $0.1326 per EA under NDC 24979053301. Its NADAC has been published 477 times since Aug 16, 2017.
FDA first approved this application on Jun 2, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
1 mg/1
Manufacturer
Upsher-Smith Laboratories LLCNDC
24979053301
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
GUANFACINEApproval Type
Generic (ANDA)
FDA Application
ANDA201408FDA Approved
6/2/2015
TE Code
AB
On Market Since
7/7/2017
Pharmacological Classes
Price Statistics
The NADAC for GUANFACINE HCL ER 1 MG TABLET has been published 477 times since Aug 16, 2017, and over the history we have for it it has declined 78.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1326 per EA |
|---|---|
| All-time high | $0.6206 (Oct 11, 2017) |
| All-time low | $0.1325 (Aug 19, 2026) |
| 52-week high | $0.1798 |
| 52-week low | $0.1325 |
| Median price | $0.2555 |
| Average price | $0.2925 |
| Largest weekly change | +33.3% (Jun 19, 2024) |
| Weeks tracked | 477 |
| Tracking since | Aug 16, 2017 |
Generic Alternatives
The matcher finds 13 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 0% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Upsher-Smith Laboratories LLC manufacturer profile
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Drug market
Guanfacine market comparison
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Therapeutic class
Central alpha-2 Adrenergic Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of GUANFACINE HCL ER 1 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for GUANFACINE HCL ER 1 MG TABLET, manufactured by Upsher-Smith Laboratories LLC, is $0.1326 per EA (NDC 24979053301), effective Sep 30, 2026.
How has the price of GUANFACINE HCL ER 1 MG TABLET changed over time?
Over the history we have for it, the NADAC for GUANFACINE HCL ER 1 MG TABLET has declined 78.6%. It has been tracked across 477 weekly CMS publications since Aug 16, 2017.
What are the highest and lowest recorded NADAC prices for GUANFACINE HCL ER 1 MG TABLET?
Since Aug 16, 2017, the NADAC for GUANFACINE HCL ER 1 MG TABLET has ranged from a low of $0.1325 (Aug 19, 2026) to a high of $0.6206 (Oct 11, 2017), with a median of $0.2555 per EA.
Are there cheaper alternatives to GUANFACINE HCL ER 1 MG TABLET?
Yes. 13 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, GUANFACINE HCL ER 1 MG TABLET, is $0.1325 per EA — about 0% below GUANFACINE HCL ER 1 MG TABLET.
Who manufactures GUANFACINE HCL ER 1 MG TABLET?
GUANFACINE HCL ER 1 MG TABLET (NDC 24979053301) is labeled by Upsher-Smith Laboratories LLC, and CMS classifies it as a generic product.