Product Information

DAPTOMYCIN 500 MG VIAL is a generic product labeled by Sagent Pharmaceuticals, priced at $22.6865 per EA under NDC 25021017415. Its NADAC has been published 123 times since Apr 17, 2024.

FDA first approved this application on Nov 15, 2019. Its Orange Book therapeutic-equivalence code is AP.

DAPTOMYCIN 500 MG VIAL

daptomycin
$22.6865per EA

Strength

50 mg/mL

NDC

25021017415

Classification

Generic

Dosage Form

INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION

Route

INTRAVENOUS

Effective Date

8/19/2026

Active Ingredients

DAPTOMYCIN

Approval Type

Generic (ANDA)

FDA Application

ANDA207104

FDA Approved

11/15/2019

TE Code

AP

On Market Since

11/15/2019

Pharmacological Classes

Price Statistics

The NADAC for DAPTOMYCIN 500 MG VIAL has been published 123 times since Apr 17, 2024, and over the history we have for it it has declined 8.7%. The table below summarizes its recorded NADAC range and movement.

Current price$22.6865 per EA
All-time high$28.3900 (Sep 11, 2024)
All-time low$20.1020 (Oct 22, 2025)
52-week high$24.2743
52-week low$20.1020
Median price$21.9840
Average price$22.7536
Largest weekly change-17.2% (Oct 22, 2025)
Weeks tracked123
Tracking sinceApr 17, 2024

Price History

1W

+8.9%

1M

+8.9%

3M

+3.8%

6M

+9.2%

1Y

-6.5%

3Y

N/A

5Y

N/A

All

-8.7%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of DAPTOMYCIN 500 MG VIAL?

The current National Average Drug Acquisition Cost (NADAC) for DAPTOMYCIN 500 MG VIAL, manufactured by Sagent Pharmaceuticals, is $22.6865 per EA (NDC 25021017415), effective Aug 19, 2026.

How has the price of DAPTOMYCIN 500 MG VIAL changed over time?

Over the history we have for it, the NADAC for DAPTOMYCIN 500 MG VIAL has declined 8.7%. It has been tracked across 123 weekly CMS publications since Apr 17, 2024.

What are the highest and lowest recorded NADAC prices for DAPTOMYCIN 500 MG VIAL?

Since Apr 17, 2024, the NADAC for DAPTOMYCIN 500 MG VIAL has ranged from a low of $20.1020 (Oct 22, 2025) to a high of $28.3900 (Sep 11, 2024), with a median of $21.9840 per EA.

Are there cheaper alternatives to DAPTOMYCIN 500 MG VIAL?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as DAPTOMYCIN 500 MG VIAL in a comparable dosage form, but none are currently priced below it.

Who manufactures DAPTOMYCIN 500 MG VIAL?

DAPTOMYCIN 500 MG VIAL (NDC 25021017415) is labeled by Sagent Pharmaceuticals, and CMS classifies it as a generic product.