Product Information
BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB is a generic product labeled by Unichem Pharmaceuticals (USA) Inc., priced at $0.2133 per EA under NDC 29300018701. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Jul 28, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB
bisoprolol fumarate and hydrochlorothiazideStrength
2.5; 6.25 mg/1; mg/1
Manufacturer
Unichem Pharmaceuticals (USA) Inc.NDC
29300018701
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
BISOPROLOL FUMARATE; HYDROCHLOROTHIAZIDEApproval Type
Generic (ANDA)
FDA Application
ANDA079106FDA Approved
7/28/2010
TE Code
AB
On Market Since
10/12/2010
Pharmacological Classes
Price Statistics
The NADAC for BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB has been published 671 times since Nov 28, 2013, and over the history we have for it it has risen 140.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2133 per EA |
|---|---|
| All-time high | $0.4799 (May 15, 2019) |
| All-time low | $0.0618 (Apr 19, 2017) |
| 52-week high | $0.2146 |
| 52-week low | $0.1855 |
| Median price | $0.2113 |
| Average price | $0.2323 |
| Largest weekly change | +316.7% (Aug 22, 2018) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Unichem Pharmaceuticals (USA) Inc. manufacturer profile
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Drug market
bisoprolol fumarate and hydrochlorothiazide market comparison
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Therapeutic class
Thiazide Diuretic class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB?
The current National Average Drug Acquisition Cost (NADAC) for BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB, manufactured by Unichem Pharmaceuticals (USA) Inc., is $0.2133 per EA (NDC 29300018701), effective Sep 30, 2026.
How has the price of BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB changed over time?
Over the history we have for it, the NADAC for BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB has risen 140.0%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB?
Since Nov 28, 2013, the NADAC for BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB has ranged from a low of $0.0618 (Apr 19, 2017) to a high of $0.4799 (May 15, 2019), with a median of $0.2113 per EA.
Are there cheaper alternatives to BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB in a comparable dosage form, but none are currently priced below it.
Who manufactures BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB?
BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB (NDC 29300018701) is labeled by Unichem Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.