Product Information
HYDROCHLOROTHIAZIDE 25 MG TAB is a generic product labeled by Unichem Pharmaceuticals (USA) Inc., priced at $0.0115 per EA under NDC 29300012810. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Aug 15, 2008. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Unichem Pharmaceuticals (USA) Inc.NDC
29300012810
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
HYDROCHLOROTHIAZIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040907FDA Approved
8/15/2008
TE Code
AB
On Market Since
8/15/2008
Pharmacological Classes
Price Statistics
The NADAC for HYDROCHLOROTHIAZIDE 25 MG TAB has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 42.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0115 per EA |
|---|---|
| All-time high | $0.0200 (Dec 11, 2013) |
| All-time low | $0.0081 (Oct 17, 2018) |
| 52-week high | $0.0124 |
| 52-week low | $0.0115 |
| Median price | $0.0129 |
| Average price | $0.0129 |
| Largest weekly change | +26.2% (Aug 21, 2024) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 9 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Unichem Pharmaceuticals (USA) Inc. manufacturer profile
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Drug market
Hydrochlorothiazide market comparison
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Therapeutic class
Thiazide Diuretic class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of HYDROCHLOROTHIAZIDE 25 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCHLOROTHIAZIDE 25 MG TAB, manufactured by Unichem Pharmaceuticals (USA) Inc., is $0.0115 per EA (NDC 29300012810), effective Sep 30, 2026.
How has the price of HYDROCHLOROTHIAZIDE 25 MG TAB changed over time?
Over the history we have for it, the NADAC for HYDROCHLOROTHIAZIDE 25 MG TAB has declined 42.3%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for HYDROCHLOROTHIAZIDE 25 MG TAB?
Since Nov 28, 2013, the NADAC for HYDROCHLOROTHIAZIDE 25 MG TAB has ranged from a low of $0.0081 (Oct 17, 2018) to a high of $0.0200 (Dec 11, 2013), with a median of $0.0129 per EA.
Are there cheaper alternatives to HYDROCHLOROTHIAZIDE 25 MG TAB?
9 manufacturers publish a NADAC-priced product with the same active ingredient and strength as HYDROCHLOROTHIAZIDE 25 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures HYDROCHLOROTHIAZIDE 25 MG TAB?
HYDROCHLOROTHIAZIDE 25 MG TAB (NDC 29300012810) is labeled by Unichem Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.