Product Information

DEMECLOCYCLINE 300 MG TABLET is a generic product labeled by Epic Pharma LLC, priced at $3.0577 per EA under NDC 42806014448. Its NADAC has been published 350 times since Feb 10, 2016.

FDA first approved this application on Aug 18, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

DEMECLOCYCLINE 300 MG TABLET

Demeclocycline Hydrochloride
$3.0577per EA

Strength

300 mg/1

Manufacturer

Epic Pharma LLC

NDC

42806014448

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA065447

FDA Approved

8/18/2015

TE Code

AB

On Market Since

2/2/2015

Pharmacological Classes

Price Statistics

The NADAC for DEMECLOCYCLINE 300 MG TABLET has been published 350 times since Feb 10, 2016, and over the history we have for it it has declined 68.0%. The table below summarizes its recorded NADAC range and movement.

Current price$3.0577 per EA
All-time high$9.9346 (Dec 15, 2021)
All-time low$3.0577 (Aug 19, 2026)
52-week high$5.9961
52-week low$3.0577
Median price$6.3527
Average price$6.8726
Largest weekly change+86.9% (Dec 23, 2020)
Weeks tracked350
Tracking sinceFeb 10, 2016

Price History

1W

-5.5%

1M

-5.5%

3M

-12.0%

6M

-49.0%

1Y

-42.1%

3Y

-69.2%

5Y

-69.2%

All

-68.0%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DEMECLOCYCLINE 300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for DEMECLOCYCLINE 300 MG TABLET, manufactured by Epic Pharma LLC, is $3.0577 per EA (NDC 42806014448), effective Aug 19, 2026.

How has the price of DEMECLOCYCLINE 300 MG TABLET changed over time?

Over the history we have for it, the NADAC for DEMECLOCYCLINE 300 MG TABLET has declined 68.0%. It has been tracked across 350 weekly CMS publications since Feb 10, 2016.

What are the highest and lowest recorded NADAC prices for DEMECLOCYCLINE 300 MG TABLET?

Since Feb 10, 2016, the NADAC for DEMECLOCYCLINE 300 MG TABLET has ranged from a low of $3.0577 (Aug 19, 2026) to a high of $9.9346 (Dec 15, 2021), with a median of $6.3527 per EA.

Are there cheaper alternatives to DEMECLOCYCLINE 300 MG TABLET?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as DEMECLOCYCLINE 300 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures DEMECLOCYCLINE 300 MG TABLET?

DEMECLOCYCLINE 300 MG TABLET (NDC 42806014448) is labeled by Epic Pharma LLC, and CMS classifies it as a generic product.