Product Information
CLOBETASOL 0.05% OINTMENT is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.1383 per GM under NDC 43386009660. Its NADAC has been published 379 times since Jul 3, 2019.
FDA first approved this application on May 4, 2018. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Lupin Pharmaceuticals Inc.NDC
43386009660
Classification
Generic
Dosage Form
OINTMENT
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA208841FDA Approved
5/4/2018
TE Code
AB
On Market Since
6/2/2018
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL 0.05% OINTMENT has been published 379 times since Jul 3, 2019, and over the history we have for it it has declined 83.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1383 per GM |
|---|---|
| All-time high | $0.8216 (Mar 11, 2020) |
| All-time low | $0.1183 (Jul 22, 2026) |
| 52-week high | $0.1644 |
| 52-week low | $0.1183 |
| Median price | $0.2952 |
| Average price | $0.3899 |
| Largest weekly change | +62.6% (Aug 21, 2024) |
| Weeks tracked | 379 |
| Tracking since | Jul 3, 2019 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 22% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Lupin Pharmaceuticals Inc. manufacturer profile
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Drug market
clobetasol propionate market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CLOBETASOL 0.05% OINTMENT?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% OINTMENT, manufactured by Lupin Pharmaceuticals Inc., is $0.1383 per GM (NDC 43386009660), effective Sep 30, 2026.
How has the price of CLOBETASOL 0.05% OINTMENT changed over time?
Over the history we have for it, the NADAC for CLOBETASOL 0.05% OINTMENT has declined 83.2%. It has been tracked across 379 weekly CMS publications since Jul 3, 2019.
What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% OINTMENT?
Since Jul 3, 2019, the NADAC for CLOBETASOL 0.05% OINTMENT has ranged from a low of $0.1183 (Jul 22, 2026) to a high of $0.8216 (Mar 11, 2020), with a median of $0.2952 per GM.
Are there cheaper alternatives to CLOBETASOL 0.05% OINTMENT?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL 0.05% OINTMENT, is $0.1083 per GM — about 22% below CLOBETASOL 0.05% OINTMENT.
Who manufactures CLOBETASOL 0.05% OINTMENT?
CLOBETASOL 0.05% OINTMENT (NDC 43386009660) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.