Clobetasol Propionate

Clobetasol Propionate is used to treat dermatitis, facial dermatoses, foot dermatoses, hand dermatoses, inflammation and leg dermatoses, per the National Library of Medicine's MED-RT classification. The brand product was first FDA-approved on Dec 27, 1985, and the first generic was approved Feb 16, 1994. FDA's Orange Book lists 44 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $127 million on Clobetasol Propionate across 2.8 million claims for 1.5 million beneficiaries.

Clobetasol Propionate is available as 143 NDCs from 23 manufacturers (138 generic, 5 brand), with NADAC prices from $0.11 to $2.25 per GM — the most expensive product costs about 20× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.