Product Information

DIFLUPREDNATE 0.05% EYE DROP is a generic product labeled by Dr. Reddy's Laboratories Inc., priced at $8.9184 per ML under NDC 43598058811. Its NADAC has been published 184 times since Feb 15, 2023.

FDA first approved this application on Nov 16, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

DIFLUPREDNATE 0.05% EYE DROP

Difluprednate Ophthalmic
$8.9184per ML

Strength

.5 mg/mL

NDC

43598058811

Classification

Generic

Dosage Form

EMULSION

Route

OPHTHALMIC

Effective Date

8/19/2026

Active Ingredients

DIFLUPREDNATE

Approval Type

Generic (ANDA)

FDA Application

ANDA214894

FDA Approved

11/16/2022

TE Code

AB

On Market Since

12/25/2022

Price Statistics

The NADAC for DIFLUPREDNATE 0.05% EYE DROP has been published 184 times since Feb 15, 2023, and over the history we have for it it has declined 47.8%. The table below summarizes its recorded NADAC range and movement.

Current price$8.9184 per ML
All-time high$22.4376 (Mar 15, 2023)
All-time low$7.0479 (Jun 17, 2026)
52-week high$11.3753
52-week low$7.0479
Median price$12.5868
Average price$13.5623
Largest weekly change+46.0% (Aug 21, 2024)
Weeks tracked184
Tracking sinceFeb 15, 2023

Price History

1W

+20.4%

1M

+26.5%

3M

+10.0%

6M

-8.9%

1Y

-21.6%

3Y

-52.9%

5Y

N/A

All

-47.8%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

Related Drugs

Same classification

No related drugs found.

Frequently asked questions

What is the NADAC price of DIFLUPREDNATE 0.05% EYE DROP?

The current National Average Drug Acquisition Cost (NADAC) for DIFLUPREDNATE 0.05% EYE DROP, manufactured by Dr. Reddy's Laboratories Inc., is $8.9184 per ML (NDC 43598058811), effective Aug 19, 2026.

How has the price of DIFLUPREDNATE 0.05% EYE DROP changed over time?

Over the history we have for it, the NADAC for DIFLUPREDNATE 0.05% EYE DROP has declined 47.8%. It has been tracked across 184 weekly CMS publications since Feb 15, 2023.

What are the highest and lowest recorded NADAC prices for DIFLUPREDNATE 0.05% EYE DROP?

Since Feb 15, 2023, the NADAC for DIFLUPREDNATE 0.05% EYE DROP has ranged from a low of $7.0479 (Jun 17, 2026) to a high of $22.4376 (Mar 15, 2023), with a median of $12.5868 per ML.

Are there cheaper alternatives to DIFLUPREDNATE 0.05% EYE DROP?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as DIFLUPREDNATE 0.05% EYE DROP in a comparable dosage form, but none are currently priced below it.

Who manufactures DIFLUPREDNATE 0.05% EYE DROP?

DIFLUPREDNATE 0.05% EYE DROP (NDC 43598058811) is labeled by Dr. Reddy's Laboratories Inc., and CMS classifies it as a generic product.