Product Information
REBIF 44 MCG/0.5 ML SYRINGE is a brand product labeled by EMD Serono, Inc., priced at $1849.8837 per ML under NDC 44087004403. Its NADAC has been published 498 times since Nov 28, 2013.
Strength
44 ug/.5mL
Manufacturer
EMD Serono, Inc.NDC
44087004403
Classification
Brand
Dosage Form
INJECTION, SOLUTION
Route
SUBCUTANEOUS
Effective Date
1/3/2026
Active Ingredients
INTERFERON BETA-1AApproval Type
Biologic (BLA)
FDA Application
BLA103780On Market Since
3/7/2002
Pharmacological Classes
Price Statistics
The NADAC for REBIF 44 MCG/0.5 ML SYRINGE has been published 498 times since Nov 28, 2013, and over the history we have for it it has risen 151.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1849.8837 per ML |
|---|---|
| All-time high | $1849.8837 (Mar 11, 2026) |
| All-time low | $735.4887 (Nov 28, 2013) |
| 52-week high | $1849.8837 |
| 52-week low | $1778.7344 |
| Median price | $1182.6427 |
| Average price | $1208.6636 |
| Largest weekly change | +18.4% (Oct 23, 2024) |
| Weeks tracked | 498 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
+4.0%
3Y
+28.3%
5Y
+28.3%
All
+151.5%
Last surveyed Mar 11, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the interferon beta-1a market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
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Manufacturer
EMD Serono, Inc. manufacturer profile
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Drug market
interferon beta-1a market comparison
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of REBIF 44 MCG/0.5 ML SYRINGE?
The current National Average Drug Acquisition Cost (NADAC) for REBIF 44 MCG/0.5 ML SYRINGE, manufactured by EMD Serono, Inc., is $1849.8837 per ML (NDC 44087004403), effective Mar 11, 2026.
How has the price of REBIF 44 MCG/0.5 ML SYRINGE changed over time?
Over the history we have for it, the NADAC for REBIF 44 MCG/0.5 ML SYRINGE has risen 151.5%. It has been tracked across 498 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for REBIF 44 MCG/0.5 ML SYRINGE?
Since Nov 28, 2013, the NADAC for REBIF 44 MCG/0.5 ML SYRINGE has ranged from a low of $735.4887 (Nov 28, 2013) to a high of $1849.8837 (Mar 11, 2026), with a median of $1182.6427 per ML.
Are there cheaper alternatives to REBIF 44 MCG/0.5 ML SYRINGE?
No other NADAC-published product currently shares the active ingredient and strength of REBIF 44 MCG/0.5 ML SYRINGE in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures REBIF 44 MCG/0.5 ML SYRINGE?
REBIF 44 MCG/0.5 ML SYRINGE (NDC 44087004403) is labeled by EMD Serono, Inc., and CMS classifies it as a brand product.