Product Information
DESOXIMETASONE 0.25% CREAM is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $0.3847 per GM under NDC 45802049535. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Jul 1, 2003. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2.5 mg/g
Manufacturer
Padagis Israel Pharmaceuticals LtdNDC
45802049535
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
DESOXIMETASONEApproval Type
Generic (ANDA)
FDA Application
ANDA076510FDA Approved
7/1/2003
TE Code
AB
On Market Since
10/24/2006
Pharmacological Classes
Price Statistics
The NADAC for DESOXIMETASONE 0.25% CREAM has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 78.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3847 per GM |
|---|---|
| All-time high | $2.4672 (Jan 13, 2016) |
| All-time low | $0.3770 (Aug 20, 2025) |
| 52-week high | $0.4846 |
| 52-week low | $0.3770 |
| Median price | $1.1710 |
| Average price | $1.1319 |
| Largest weekly change | +108.7% (Mar 18, 2020) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 18% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DESOXIMETASONE 0.25% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for DESOXIMETASONE 0.25% CREAM, manufactured by Padagis Israel Pharmaceuticals Ltd, is $0.3847 per GM (NDC 45802049535), effective Aug 19, 2026.
How has the price of DESOXIMETASONE 0.25% CREAM changed over time?
Over the history we have for it, the NADAC for DESOXIMETASONE 0.25% CREAM has declined 78.5%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for DESOXIMETASONE 0.25% CREAM?
Since Nov 28, 2013, the NADAC for DESOXIMETASONE 0.25% CREAM has ranged from a low of $0.3770 (Aug 20, 2025) to a high of $2.4672 (Jan 13, 2016), with a median of $1.1710 per GM.
Are there cheaper alternatives to DESOXIMETASONE 0.25% CREAM?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DESOXIMETASONE 0.25% CREAM, is $0.3174 per GM — about 18% below DESOXIMETASONE 0.25% CREAM.
Who manufactures DESOXIMETASONE 0.25% CREAM?
DESOXIMETASONE 0.25% CREAM (NDC 45802049535) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.