Product Information

GNP ANTI-DIARRHEAL-GAS CPLT is a generic product labeled by AmerisourceBergen, priced at $0.2867 per EA under NDC 46122062062. Its NADAC has been published 257 times since Sep 22, 2021.

FDA first approved this application on Sep 5, 2018.

GNP ANTI-DIARRHEAL-GAS CPLT

loperamide hydrochloride, simethicone
$0.2867per EA
OTC

Strength

125; 2 mg/1; mg/1

Manufacturer

AmerisourceBergen

NDC

46122062062

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA209837

FDA Approved

9/5/2018

On Market Since

6/24/2020

Pharmacological Classes

Opioid Agonist
Opioid Agonists
Skin Barrier Activity

Price Statistics

The NADAC for GNP ANTI-DIARRHEAL-GAS CPLT has been published 257 times since Sep 22, 2021, and over the history we have for it it has risen 6.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2867 per EA
All-time high$0.3621 (Sep 13, 2023)
All-time low$0.2638 (Jun 18, 2025)
52-week high$0.3073
52-week low$0.2743
Median price$0.2919
Average price$0.2919
Largest weekly change+21.9% (Aug 23, 2023)
Weeks tracked257
Tracking sinceSep 22, 2021

Price History

1W

-1.0%

1M

-1.0%

3M

-1.0%

6M

-5.3%

1Y

+4.5%

3Y

-3.5%

5Y

N/A

All

+6.1%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of GNP ANTI-DIARRHEAL-GAS CPLT?

The current National Average Drug Acquisition Cost (NADAC) for GNP ANTI-DIARRHEAL-GAS CPLT, manufactured by AmerisourceBergen, is $0.2867 per EA (NDC 46122062062), effective Aug 19, 2026.

How has the price of GNP ANTI-DIARRHEAL-GAS CPLT changed over time?

Over the history we have for it, the NADAC for GNP ANTI-DIARRHEAL-GAS CPLT has risen 6.1%. It has been tracked across 257 weekly CMS publications since Sep 22, 2021.

What are the highest and lowest recorded NADAC prices for GNP ANTI-DIARRHEAL-GAS CPLT?

Since Sep 22, 2021, the NADAC for GNP ANTI-DIARRHEAL-GAS CPLT has ranged from a low of $0.2638 (Jun 18, 2025) to a high of $0.3621 (Sep 13, 2023), with a median of $0.2919 per EA.

Are there cheaper alternatives to GNP ANTI-DIARRHEAL-GAS CPLT?

2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as GNP ANTI-DIARRHEAL-GAS CPLT in a comparable dosage form, but none are currently priced below it.

Who manufactures GNP ANTI-DIARRHEAL-GAS CPLT?

GNP ANTI-DIARRHEAL-GAS CPLT (NDC 46122062062) is labeled by AmerisourceBergen, and CMS classifies it as a generic product.