Product Information
GNP ANTI-DIARRHEAL-GAS CPLT is a generic product labeled by AmerisourceBergen, priced at $0.2857 per EA under NDC 46122062062. Its NADAC has been published 263 times since Sep 22, 2021.
FDA first approved this application on Sep 5, 2018.
Strength
125; 2 mg/1; mg/1
Manufacturer
AmerisourceBergenNDC
46122062062
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
DIMETHICONE; LOPERAMIDE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA209837FDA Approved
9/5/2018
On Market Since
6/24/2020
Pharmacological Classes
Price Statistics
The NADAC for GNP ANTI-DIARRHEAL-GAS CPLT has been published 263 times since Sep 22, 2021, and over the history we have for it it has risen 5.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2857 per EA |
|---|---|
| All-time high | $0.3621 (Sep 13, 2023) |
| All-time low | $0.2638 (Jun 18, 2025) |
| 52-week high | $0.3073 |
| 52-week low | $0.2857 |
| Median price | $0.2903 |
| Average price | $0.2917 |
| Largest weekly change | +21.9% (Aug 23, 2023) |
| Weeks tracked | 263 |
| Tracking since | Sep 22, 2021 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
AmerisourceBergen manufacturer profile
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Drug market
loperamide hydrochloride, simethicone market comparison
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Therapeutic class
Opioid Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of GNP ANTI-DIARRHEAL-GAS CPLT?
The current National Average Drug Acquisition Cost (NADAC) for GNP ANTI-DIARRHEAL-GAS CPLT, manufactured by AmerisourceBergen, is $0.2857 per EA (NDC 46122062062), effective Sep 30, 2026.
How has the price of GNP ANTI-DIARRHEAL-GAS CPLT changed over time?
Over the history we have for it, the NADAC for GNP ANTI-DIARRHEAL-GAS CPLT has risen 5.7%. It has been tracked across 263 weekly CMS publications since Sep 22, 2021.
What are the highest and lowest recorded NADAC prices for GNP ANTI-DIARRHEAL-GAS CPLT?
Since Sep 22, 2021, the NADAC for GNP ANTI-DIARRHEAL-GAS CPLT has ranged from a low of $0.2638 (Jun 18, 2025) to a high of $0.3621 (Sep 13, 2023), with a median of $0.2903 per EA.
Are there cheaper alternatives to GNP ANTI-DIARRHEAL-GAS CPLT?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as GNP ANTI-DIARRHEAL-GAS CPLT in a comparable dosage form, but none are currently priced below it.
Who manufactures GNP ANTI-DIARRHEAL-GAS CPLT?
GNP ANTI-DIARRHEAL-GAS CPLT (NDC 46122062062) is labeled by AmerisourceBergen, and CMS classifies it as a generic product.