Product Information
GNP PAIN RLF PM 25-500 MG CPLT is a generic product labeled by AmerisourceBergen, priced at $0.0447 per EA under NDC 46122070778. Its NADAC has been published 177 times since Feb 8, 2023.
Strength
500; 25 mg/1; mg/1
Manufacturer
AmerisourceBergenNDC
46122070778
Classification
Generic
Dosage Form
TABLET, COATED
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
ACETAMINOPHEN; DIPHENHYDRAMINE HYDROCHLORIDEApproval Type
OTC MONOGRAPH DRUG
FDA Application
M013On Market Since
6/1/2022
Pharmacological Classes
Price Statistics
The NADAC for GNP PAIN RLF PM 25-500 MG CPLT has been published 177 times since Feb 8, 2023, and over the history we have for it it has declined 6.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0447 per EA |
|---|---|
| All-time high | $0.0552 (Dec 11, 2024) |
| All-time low | $0.0436 (Feb 19, 2025) |
| 52-week high | $0.0479 |
| 52-week low | $0.0447 |
| Median price | $0.0471 |
| Average price | $0.0475 |
| Largest weekly change | -12.3% (Jul 19, 2023) |
| Weeks tracked | 177 |
| Tracking since | Feb 8, 2023 |
Generic Alternatives
The matcher finds 4 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 4 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 1% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of GNP PAIN RLF PM 25-500 MG CPLT?
The current National Average Drug Acquisition Cost (NADAC) for GNP PAIN RLF PM 25-500 MG CPLT, manufactured by AmerisourceBergen, is $0.0447 per EA (NDC 46122070778), effective Jun 24, 2026.
How has the price of GNP PAIN RLF PM 25-500 MG CPLT changed over time?
Over the history we have for it, the NADAC for GNP PAIN RLF PM 25-500 MG CPLT has declined 6.6%. It has been tracked across 177 weekly CMS publications since Feb 8, 2023.
What are the highest and lowest recorded NADAC prices for GNP PAIN RLF PM 25-500 MG CPLT?
Since Feb 8, 2023, the NADAC for GNP PAIN RLF PM 25-500 MG CPLT has ranged from a low of $0.0436 (Feb 19, 2025) to a high of $0.0552 (Dec 11, 2024), with a median of $0.0471 per EA.
Are there cheaper alternatives to GNP PAIN RLF PM 25-500 MG CPLT?
Yes. 4 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, HM PAIN RELIEVER PM GELTAB, is $0.0441 per EA — about 1% below GNP PAIN RLF PM 25-500 MG CPLT.
Who manufactures GNP PAIN RLF PM 25-500 MG CPLT?
GNP PAIN RLF PM 25-500 MG CPLT (NDC 46122070778) is labeled by AmerisourceBergen, and CMS classifies it as a generic product.
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