Product Information

GNP ACETAMINOPHEN-IBUPROFEN 250-125 MG TABLET is a generic product labeled by AmerisourceBergen, priced at $0.1058 per EA under NDC 46122074268. Its NADAC has been published 127 times since Mar 20, 2024.

FDA first approved this application on Aug 1, 2023.

GNP ACETAMINOPHEN-IBUPROFEN 250-125 MG TABLET

Acetaminophen and Ibuprofen
$0.1058per EA
OTC

Strength

250; 125 mg/1; mg/1

Manufacturer

AmerisourceBergen

NDC

46122074268

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

ACETAMINOPHEN; IBUPROFEN

Approval Type

Generic (ANDA)

FDA Application

ANDA216999

FDA Approved

8/1/2023

On Market Since

9/8/2023

Pharmacological Classes

Anti-Inflammatory Agents
Non-Steroidal
Cyclooxygenase Inhibitors
Nonsteroidal Anti-inflammatory Drug

Price Statistics

The NADAC for GNP ACETAMINOPHEN-IBUPROFEN 250-125 MG TABLET has been published 127 times since Mar 20, 2024, and over the history we have for it it has risen 67.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1058 per EA
All-time high$0.1086 (Jul 16, 2025)
All-time low$0.0610 (May 22, 2024)
52-week high$0.1058
52-week low$0.0839
Median price$0.0894
Average price$0.0863
Largest weekly change+15.2% (Jul 17, 2024)
Weeks tracked127
Tracking sinceMar 20, 2024

Price History

1W

+5.8%

1M

+5.8%

3M

+25.4%

6M

+17.6%

1Y

+15.3%

3Y

N/A

5Y

N/A

All

+67.8%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 20% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of GNP ACETAMINOPHEN-IBUPROFEN 250-125 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for GNP ACETAMINOPHEN-IBUPROFEN 250-125 MG TABLET, manufactured by AmerisourceBergen, is $0.1058 per EA (NDC 46122074268), effective Aug 19, 2026.

How has the price of GNP ACETAMINOPHEN-IBUPROFEN 250-125 MG TABLET changed over time?

Over the history we have for it, the NADAC for GNP ACETAMINOPHEN-IBUPROFEN 250-125 MG TABLET has risen 67.8%. It has been tracked across 127 weekly CMS publications since Mar 20, 2024.

What are the highest and lowest recorded NADAC prices for GNP ACETAMINOPHEN-IBUPROFEN 250-125 MG TABLET?

Since Mar 20, 2024, the NADAC for GNP ACETAMINOPHEN-IBUPROFEN 250-125 MG TABLET has ranged from a low of $0.0610 (May 22, 2024) to a high of $0.1086 (Jul 16, 2025), with a median of $0.0894 per EA.

Are there cheaper alternatives to GNP ACETAMINOPHEN-IBUPROFEN 250-125 MG TABLET?

Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ACETAMINOPHEN-IBUPROFEN 250-125 MG CAPLET, is $0.0844 per EA — about 20% below GNP ACETAMINOPHEN-IBUPROFEN 250-125 MG TABLET.

Who manufactures GNP ACETAMINOPHEN-IBUPROFEN 250-125 MG TABLET?

GNP ACETAMINOPHEN-IBUPROFEN 250-125 MG TABLET (NDC 46122074268) is labeled by AmerisourceBergen, and CMS classifies it as a generic product.