Product Information
GNP PM PAIN RLF 25-500 MG CPLT is a generic product labeled by AmerisourceBergen, priced at $0.0439 per EA under NDC 46122079969. Its NADAC has been published 74 times since May 7, 2025.
Strength
500; 25 mg/1; mg/1
Manufacturer
AmerisourceBergenNDC
46122079969
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ACETAMINOPHEN; DIPHENHYDRAMINE HYDROCHLORIDEApproval Type
OTC MONOGRAPH DRUG
FDA Application
M013On Market Since
10/1/2024
Pharmacological Classes
Price Statistics
The NADAC for GNP PM PAIN RLF 25-500 MG CPLT has been published 74 times since May 7, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0439 per EA |
|---|---|
| All-time high | $0.0479 (Jul 16, 2025) |
| All-time low | $0.0439 (Sep 23, 2026) |
| 52-week high | $0.0470 |
| 52-week low | $0.0439 |
| Median price | $0.0464 |
| Average price | $0.0461 |
| Largest weekly change | +7.3% (May 21, 2025) |
| Weeks tracked | 74 |
| Tracking since | May 7, 2025 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
AmerisourceBergen manufacturer profile
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Drug market
Acetaminophen, Diphenhydramine HCl market comparison
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Therapeutic class
Histamine-1 Receptor Antagonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of GNP PM PAIN RLF 25-500 MG CPLT?
The current National Average Drug Acquisition Cost (NADAC) for GNP PM PAIN RLF 25-500 MG CPLT, manufactured by AmerisourceBergen, is $0.0439 per EA (NDC 46122079969), effective Sep 30, 2026.
How has the price of GNP PM PAIN RLF 25-500 MG CPLT changed over time?
Over the history we have for it, the NADAC for GNP PM PAIN RLF 25-500 MG CPLT has held within roughly two percent of its current level. It has been tracked across 74 weekly CMS publications since May 7, 2025.
What are the highest and lowest recorded NADAC prices for GNP PM PAIN RLF 25-500 MG CPLT?
Since May 7, 2025, the NADAC for GNP PM PAIN RLF 25-500 MG CPLT has ranged from a low of $0.0439 (Sep 23, 2026) to a high of $0.0479 (Jul 16, 2025), with a median of $0.0464 per EA.
Are there cheaper alternatives to GNP PM PAIN RLF 25-500 MG CPLT?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as GNP PM PAIN RLF 25-500 MG CPLT in a comparable dosage form, but none are currently priced below it.
Who manufactures GNP PM PAIN RLF 25-500 MG CPLT?
GNP PM PAIN RLF 25-500 MG CPLT (NDC 46122079969) is labeled by AmerisourceBergen, and CMS classifies it as a generic product.