Product Information

IBUPROFEN 400 MG TABLET is a generic product labeled by Time-Cap Labs Inc., priced at $0.0391 per EA under NDC 49483060250. Its NADAC has been published 536 times since May 18, 2016.

FDA first approved this application on Dec 21, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

IBUPROFEN 400 MG TABLET

Ibuprofen
$0.0391per EA

Strength

400 mg/1

Manufacturer

Time-Cap Labs Inc.

NDC

49483060250

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

IBUPROFEN

Approval Type

Generic (ANDA)

FDA Application

ANDA090796

FDA Approved

12/21/2010

TE Code

AB

On Market Since

12/30/2015

Pharmacological Classes

Anti-Inflammatory Agents
Non-Steroidal
Cyclooxygenase Inhibitors
Nonsteroidal Anti-inflammatory Drug

Price Statistics

The NADAC for IBUPROFEN 400 MG TABLET has been published 536 times since May 18, 2016, and over the history we have for it it has declined 10.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0391 per EA
All-time high$0.0577 (Sep 15, 2021)
All-time low$0.0336 (Sep 19, 2018)
52-week high$0.0433
52-week low$0.0387
Median price$0.0461
Average price$0.0458
Largest weekly change-25.2% (Nov 20, 2024)
Weeks tracked536
Tracking sinceMay 18, 2016

Price History

1W

+0.5%

1M

-1.7%

3M

-4.5%

6M

+1.1%

1Y

-9.9%

3Y

-17.3%

5Y

-32.2%

All

-10.1%

Generic Alternatives

The matcher finds 14 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of IBUPROFEN 400 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for IBUPROFEN 400 MG TABLET, manufactured by Time-Cap Labs Inc., is $0.0391 per EA (NDC 49483060250), effective Aug 19, 2026.

How has the price of IBUPROFEN 400 MG TABLET changed over time?

Over the history we have for it, the NADAC for IBUPROFEN 400 MG TABLET has declined 10.1%. It has been tracked across 536 weekly CMS publications since May 18, 2016.

What are the highest and lowest recorded NADAC prices for IBUPROFEN 400 MG TABLET?

Since May 18, 2016, the NADAC for IBUPROFEN 400 MG TABLET has ranged from a low of $0.0336 (Sep 19, 2018) to a high of $0.0577 (Sep 15, 2021), with a median of $0.0461 per EA.

Are there cheaper alternatives to IBUPROFEN 400 MG TABLET?

14 manufacturers publish a NADAC-priced product with the same active ingredient and strength as IBUPROFEN 400 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures IBUPROFEN 400 MG TABLET?

IBUPROFEN 400 MG TABLET (NDC 49483060250) is labeled by Time-Cap Labs Inc., and CMS classifies it as a generic product.