Product Information
RISPERIDONE 0.25 MG ODT is a generic product labeled by Endo USA Inc., priced at $2.5528 per EA under NDC 49884021255. Its NADAC has been published 403 times since Jan 22, 2014.
FDA first approved this application on Apr 30, 2009. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.25 mg/1
Manufacturer
Endo USA Inc.NDC
49884021255
Classification
Generic
Dosage Form
TABLET, ORALLY DISINTEGRATING
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
RISPERIDONEApproval Type
Generic (ANDA)
FDA Application
ANDA077494FDA Approved
4/30/2009
TE Code
AB
On Market Since
6/1/2009
Pharmacological Classes
Price Statistics
The NADAC for RISPERIDONE 0.25 MG ODT has been published 403 times since Jan 22, 2014, and over the history we have for it it has declined 16.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.5528 per EA |
|---|---|
| All-time high | $3.0604 (Feb 11, 2015) |
| All-time low | $1.1789 (May 22, 2024) |
| 52-week high | $2.9423 |
| 52-week low | $1.8592 |
| Median price | $2.8666 |
| Average price | $2.4761 |
| Largest weekly change | +56.6% (Nov 19, 2025) |
| Weeks tracked | 403 |
| Tracking since | Jan 22, 2014 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Endo USA Inc. manufacturer profile
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Drug market
Risperidone market comparison
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Therapeutic class
Atypical Antipsychotic class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of RISPERIDONE 0.25 MG ODT?
The current National Average Drug Acquisition Cost (NADAC) for RISPERIDONE 0.25 MG ODT, manufactured by Endo USA Inc., is $2.5528 per EA (NDC 49884021255), effective Sep 30, 2026.
How has the price of RISPERIDONE 0.25 MG ODT changed over time?
Over the history we have for it, the NADAC for RISPERIDONE 0.25 MG ODT has declined 16.6%. It has been tracked across 403 weekly CMS publications since Jan 22, 2014.
What are the highest and lowest recorded NADAC prices for RISPERIDONE 0.25 MG ODT?
Since Jan 22, 2014, the NADAC for RISPERIDONE 0.25 MG ODT has ranged from a low of $1.1789 (May 22, 2024) to a high of $3.0604 (Feb 11, 2015), with a median of $2.8666 per EA.
Are there cheaper alternatives to RISPERIDONE 0.25 MG ODT?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, RISPERIDONE 0.25 MG TABLET, is $0.0368 per EA — about 99% below RISPERIDONE 0.25 MG ODT.
Who manufactures RISPERIDONE 0.25 MG ODT?
RISPERIDONE 0.25 MG ODT (NDC 49884021255) is labeled by Endo USA Inc., and CMS classifies it as a generic product.